Abstract
The clinical and histological findings are described in 12 infants (5 boys, 7 girls) suffering from congenital intracranial tumors. An enlarged head or signs of increased intracranial pressure were present at birth or within the first 12 months of life (average 5.1 months). The histological picture of the tumors (6 supratentorial, 6 infratentorial) varied. In 6 children a ventriculoperitoneal shunt was necessary; partial or total removal of the tumor was attempted in 5 infants; 4 patients received irradiation. Prognosis was poor, and survival time averaged 13 months. A short review of the literature is given; new diagnostic techniques (computed tomography, magnetic resonance imaging) allow earlier diagnosis. However, because of the size and location, successful treatment is rarely possible.
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References
Arnstein LH, Boldrey E, Naffziger HL (1951) A case report and survey of brain tumors during the neonatal period. J Neurosurg 8:315–319
Avery GB (1975) Neonatology: pathophysiology and management of the newborn. Lippincott, Philadelphia, pp 675–685
Collins VP (1955) Wilm's tumor. Its behavior and prognosis. J La State Med Soc 107:474–480
Farwell JR, Dohrmann EJ, Flannery JT (1978) Intracranial neoplasms in infants. Arch Neurol 3:533–537
Fessard C (1968) Cerebral tumors in infancy. 66 Clinicoanatomical case studies. Am J Dis Child 115:302–398
Harwood-Nash DC, Fitz CR (1976) Neuroradiology in infants and children, vol 2. Mosby, St Louis, Mo, pp 668–788
Jellinger K, Sunder-Plassmann H (1973) Connatal intracranial tumors. Neuropediatrics 4:46–64
Jellinger K, Seitelberger F (1970) Zur Neuropathologie der Hirngeschwülste im Kindesalter. Wien Med Wochenschr 47:855–861
Kim JH, Duncan C, Manuelidis EE (1985) Congenital cerebellar medulloblastoma. Surg Neurol 23:75–81
Koos WT, Miller MH (1971) Intracranial tumors of infants and children. Thieme, Stuttgart
Lemire RJ, Loeser JD, Leech RW, Alvord ED (1975) Congenital tumor of the nervous system in normal and abnormal development of the human nervous system. Harper & Row, Hagerstown, pp 344–384
Matson DD (1964) Intracranial tumors of the first two years of life. West J Surg Obstet Gynecol 72:117–122
Raimondi AJ, Tomita TI (1979) Medulloblastoma in childhood. Comparative results of partial and total resection. Child's Brain 5:310–328
Raimondi AJ, Tomita T (1983) Brain tumors during the first year of life. Child's Brain 10:193–207
Raskind R, Brigel F (1984) Brain tumors in early infancy — probably congenital in origin. J Pediatr 65:727–732
Russell DS, Rubinstein LJ (1971) Pathology of tumors of the nervous system, 3rd edn. Arnold, London, pp 5–10
Sato O, Tamura A, Sano K (1975) Brain tumors of early infants. Child's Brain 1:121–125
Sato T, Shimoda A, Takahashi T, Kurokawa H, Ando M, Goto S, Takamura H (1984) Congenital anaplastic ependymoma: a case report of familial glioma. Child's Brain 11:342–348
Solitare GB, Krigman MR (1964) Congenital intracranial neoplasm. J Neuropathol Exp Neurol 23:280–292
Sunder-Plassmann M, Jellinger K (1971) Neuroektodermale Hirngeschwülste im ersten Lebensjahr. Acta Neurochir 24:107–120
Wakai S, Arai T, Nagai M (1984) Congenital brain tumors. Surg Neurol 21:597–609
Wakany J (1971) Congenital malformations. Notes and comments. Year Book Medical Publishers, Chicago, pp 1211–1212
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Ellams, I.D., Neuhäuser, G. & Agnoli, A.L. Congenital intracranial neoplasms. Child's Nerv Syst 2, 165–168 (1986). https://doi.org/10.1007/BF00706804
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DOI: https://doi.org/10.1007/BF00706804