7.1 In the context of echocardiographic confirmation of supra-systemic pulmonary arterial hypertension in the absence of left ventricular dysfunction, a trial of inhaled nitric oxide (iNO) should be used, providing that lung recruitment is adequate. If there is no iNO response based on echocardiographic assessment or other parameters (clinical or laboratory), iNO should be stopped. | 4 | B-NR |
7.2 Milrinone should be used to treat cardiac dysfunction, particularly if it is associated with pulmonary hypertension. | 4 | B-NR |
7.3 The use of sildenafil may be considered in patients with refractory pulmonary hypertension (ie, unresponsive to iNO) or as an adjunct when weaning iNO. | 3 | B-NR |