Table 4

Daily skin morbidity scores in the period between catheter insertion and 48 hours post catheter removal

Skin morbidity scores2% CHG-70% IPA (n=87)2% CHG-aqueous (n=27)
Worst score for skin dryness throughout safety monitoring period
 Median (IQR)1 (1–1)1 (1–1)
 Range(1–2)(1–2)
 180 (92.0)26 (96.3)
 27 (8.0)1 (3.7)
 300
Worst score for erythema throughout safety monitoring period
 Median (IQR)1 (1–1)1 (1–1)
 Range(1–2)(1–2)
 172 (82.8)22 (81.5)
 215 (17.2)5 (18.5)
 300
Worst score for breakdown/excoriation throughout safety monitoring period
 Median (IQR)1 (1–1)1 (1–1)
 Range(1–2)(1–2)
 182 (94.3)25 (92.6)
 25 (5.7)2 (7.4)
 300
Worst score for totals of all three scores throughout safety monitoring period
 Median (IQR)3 (3–4)3 (3–4)
 Range(3–5)(3–5)
 365 (74.7)20 (74.1)
 420 (23.0)6 (22.2)
 52 (2.3)1 (3.7)
 ≥600
Scoring was performed at baseline, within 10-30 minutes of catheterisation, and then daily until 48 hours post catheter removal, including for any infants repatriated to another hospital with their PCVC still in situ. Skin integrity scoring was also recorded until 48 hours post antiseptic application in instances where catheterisation proved unsuccessful.
Skin scores were graded as follows:
Dryness
1=Normal, no sign of dry skin
2=Dry skin, visible scaling
3=Very dry skin, cracking/fissures
Erythema
1=No evidence of erythema
2=Visible erythema <50% of skin area exposed to antiseptic
3=Visible erythema ≥50% of skin area exposed to antiseptic
Breakdown/excoriation
1=None evident
2=Small localised areas
3=Extensive
  • CHG, chlorhexidine gluconate; IPA, isopropyl alcohol; IQR, interquartile range; PCVC, percutaneous central venous catheter.