Table 3

Bacterial species isolated via standard microbiology laboratory culture for infants with at least one positive culture result

ID noIMP allocationBlood culture(s)Exit site skin swabCatheter segment
Closest to PCVC removal (days)Blood culture resultsBefore disinfectionAfter disinfectionProximalTip
#1#2#3
12% CHG-70% IPA6.2 preNo growthNo growthCoNS: S. capitis No growthNo growthNo growth
22% CHG-70% IPAN/AN/AN/ANo growthNo growthCoNS: S. capitis No growth
32% CHG-70% IPA0.3 preMixed CoNS
(not specified)
No growthNo growthNo growthNo growthNo growth
42% CHG-70% IPAN/AN/AN/ACoNS:
S. haemolyticus
No growthNo growthNo growth
52% CHG-70% IPA0.0 postCoNS: S. epidermidis CoNS: S. capitis No growthNo growthNo growthNo growth
62% CHG-70% IPA1.8 postNo growthCoNS: S. capitis No growthNo growthNo growth
72% CHG-70% IPA0.9 postNo growthNo growthCoNS: S. capitis No growthNo growth
82% CHG-70% IPAN/AN/AN/ACoNS:
S. epidermidis
No growthNo growthNo growth
92% CHG-70% IPAN/AN/AN/AMixed CoNS (not specified)No growthNo growthNo growth
102% CHG-70% IPA1.3 postCoNS: (not specified)No growthNo growthNo growthNo growth
112% CHG-70% IPA0.0 postNo growthCoNS: S. capitis No growthNo growthNo growthNo growth
122% CHG-70% IPAN/AN/AN/ACoNS: S. capitis No growthNo growthCoNS: S. capitis
132% CHG-70% IPA1.4 postNo growthCoNS:
S. haemolyticus
No growthNo growthNo growthNo growth
14*2% CHG-70% IPA0.0 postCoNS: 1. S. haemolyticus; 2. S. epidermidis No growthCoNS: S. capitis No growthNo growthNo growth
15†2% CHG-70% IPA1.7 postCoNS: S. capitis CoNS: S. capitis No growthNo growthNo growthCoNS: S. capitis No growth
16*2% CHG-70% IPA6.1 preNo growthCoNS: S. capitis CoNS: S. capitis No growthNo growthNo growth
172% CHG-70% IPA0.2 preCoNS: S. haemolyticus No growthCoNS: S. capitis No growthNo growthNo growthNo growth
182% CHG-70% IPA5.8 preCoNS: S. haemolyticus CoNS: S. epidermidis No growthNo growthNo growthNo growthNo growth
192% CHG-70% IPAN/AN/AN/ACoNS: S. warneri No growthNo growthNo growth
202% CHG-70% IPA0.2 preNo growthCoNS: S. capitis No growthNo growthNo growthNo growthNo growth
212% CHG-70% IPAN/AN/AN/A1. CoNS: S. capitis;
2. S. aureus
No growthNo growthNo growth
222% CHG-70% IPACoNS: not specifiedMissing‡Missing‡Missing‡No growth
232% CHG-70% IPAN/AN/AN/ACoNS: S. haemolyticus No growthNo growthNo growth
242% CHG-aqueous1.7 postNo growthCoNS: S. haemolyticus No growthNo growthNo growth
252% CHG-aqueous0.0 postCoNS: S. warneri No growthNo growthNo growthNo growthNo growth
26†2% CHG-aqueous0.3 preNo growthCoNS: S. warneri No growthNo growthNo growthCoNS: S. warneri
272% CHG-aqueousN/AN/AN/ACoNS: S. haemolyticus§ No growthNo growthNo growth
282% CHG-aqueousN/AN/AN/ACoNS: S. capitis CoNS: S. capitis No growthNo growth
292% CHG-aqueous4.0 preCoNS: S. capitis No growthNo growthNo growthNo growthNo growth
302% CHG-aqueous0.5 postCoNS: 1. S. epidermidis; 2.
S. capitis
No growthNo growthMissing¶No growthNo growth
312% CHG-aqueousN/AN/AN/ACoNS: S. epidermidis No growthCoNS: S. epidermidis CoNS: S. epidermidis
  • *One of two cases of catheter-associated sepsis.

  • †One of two cases of definite catheter-related sepsis, both paired isolates confirmed via whole genome sequencing.

  • ‡Infant was transferred to a non-participating site where their line was removed.

  • §Detail of species was not captured in database, but was found post data lock.

  • ¶Sample not obtained.

  • CoNS, coagulase-negative staphylococcus; ID, identifier; IMP, Investigational Medicinal Product; N/A, not applicable because no blood culture taken between catheter insertion and 48 hours post removal; PCVC, percutaneous central venous catheter; S. aureus, Staphylococcus aureus; S. capitas, Staphylococcus capitis; S. epidermidis, Staphylococcus epidermidis; S. haemolyticus, Staphylococcus haemolyticus; S. warneri, Staphylococcus warneri.