Baseline patient characteristics (N=32)
| Patient characteristics | Surfactant nebulisation (N=16) | Standard care (N=16) |
| Demographic | ||
| Gestational age at birth (weeks) | 29.4 (29–31.1) | 30.1 (27–31.1) |
| Birth weight(g) | 1080 (930–1430) | 1140 (880–1360) |
| Male, n (%) | 9 (56) | 7 (44) |
| Prenatal | ||
| Estimated birth weight (g) | 1080 (880–1370) | 1170 (860–1360) |
| Completed antenatal steroids, n (%) | 13 (81) | 10 (63) |
| PPROM, n (%) | 6 (38) | 3 (19) |
| Chorioamnionitis, n (%) | 3 (19) | 2 (13) |
| Oligohydramnios or anhydramnios, n (%) | 3 (19) | 3 (19) |
| Preeclampsia, n (%) | 6 (38) | 4 (25) |
| IUGR, n (%) | 4 (25) | 4 (25) |
| Delivered by CS, n (%) | 16 (100) | 14 (87) |
| Postnatal | ||
| Time of cord clamping (sec) | 60 (41–60) | 60 (54–60) |
| Apgar score at 5 min | 8 (7–8) | 8 (7–9) |
| Umbilical artery pH | 7.32 (7.29–7.36) | 7.32 (7.27–7.32) |
| Dose of SN (mg/kg)* | 198 (163–241) | – |
| Start of SN (sec after birth) | 80 (64–88) | – |
| Duration of SN (min) | 13 (9–14) | – |
Unless otherwise specified, median and IQR are depicted.
*Dose of SN is based on the actual weight of the infant (measured after birth). There were no significant differences between groups.
CS, caesarean section; IUGR, intrauterine growth restriction; pCO2, partial pressure of carbon dioxide; PPROM, prolonged premature rupture of the membranes; SN, surfactant nebulisation.