Initial antibiotic treatment for early-onset neonatal sepsis and clinical evolution of infants
| All study infants (N=108) | |
| Initiation of antibiotic treatment, n (%) | 108 (100) |
| Time from birth to initiation of antibiotic treatment, n (%) | |
| <12 hours | 62 (57.4) |
| ≥12 hours | 46 (42.6) |
| Initial antibiotic treatment, n (%) | |
| Amoxicillin–gentamicin | 65 (60.2) |
| Amoxicillin–cefotaxime–gentamicin | 21 (19.4) |
| Cefotaxime–gentamicin | 14 (13.0) |
| Amoxicillin–cefotaxime–amikacin | 2 (1.9) |
| Amoxicillin–amikacin | 2 (1.9) |
| Cefotaxime–gentamicin–vancomycin | 2 (1.9) |
| Cefotaxime–amikacin | 1 (0.9) |
| Vancomycin–gentamicin | 1 (0.9) |
| Modification of antibiotic treatment, n (%) | 55 (50.9) |
| Duration of main antibiotic treatment, days, median (IQR) | |
| Sepsis | 8 (7–10) |
| Sepsis plus meningitis | 21 (21–21) |
| Transfer to another department, n (%) | 101 (93.5) |
| Neonatal intensive care unit | 73 (72.3) |
| Neonatology | 28 (27.7) |
| Age (hours) at transfer, median | 4.0 |
| Death, n (%) | 2 (1.9) |