Clinical and audiological characteristics of 54 infants with cCMV infection and failed newborn hearing screening
| Characteristics | cCMV-infected infants (n=54) |
| Infant sex, male, n (%) | 25 (46) |
| Gestational age at birth, weeks, mean (SD) | 39.3 (1.7) |
| Age at cCMV diagnosis, days, mean (SD) | 50 (24.3) |
| Birth weight mean SD (95% CI) | −0.48 (–0.72 to –0.23) |
| <–2 | 3 (6) |
| −2 to +2 | 51 (94) |
| >+2 | 0 |
| Head circumference mean SD (95% CI)* | −0.70 (–1.04 to –0.35) |
| <–2 | 6 (12) |
| −2 to +2 | 45 (88) |
| >+2 | 0 |
| Audiological outcome, n | 54 |
| Unilateral conductive hearing loss, n (%) | 3 (6) |
| Bilateral conductive hearing loss, n (%) | 3 (6) |
| SNHL, n (%) | 48 (89) |
| Unilateral SNHL, n (%) | 24 (50) |
| Bilateral SNHL, n (%) | 24 (50) |
| ABR results for SNHL | Unilateral† | Bilateral‡ |
| 24 ears (%) | 48 ears (%) | |
| Mild hearing loss (21–40 dB) | 0 | 5 (10) |
| Moderate hearing loss (41–70 dB) | 4 (17) | 9 (19) |
| Severe hearing loss (71–90 dB) | 4 (17) | 11 (23) |
| Profound hearing loss (>90 dB) | 16 (66) | 23 (48) |
*Data available for 51 infants in the first 6 months of life.
†Six ears had mixed hearing loss (conductive combined with SNHL). The hearing threshold and type of loss are registered as observed by the audiologist.
‡Fifteen ears with mixed hearing loss (conductive combined with SNHL). The hearing threshold is registered as observed by the audiologist.
ABR, auditory brainstem response; cCMV, congenital cytomegalovirus; CI, confidence interval; dB, decibel; SD, standard deviation; SNHL, sensorineural hearing loss.