Table 2

Neonatal subject demographics and scan results

ID	Gestational age (weeks, days)+sex	Clinical diagnosis	SOC imaging	Age at scan (days)	Weight during scan (kg)	SOC key findings	Portable MRI key findings
1	27, 2 F	Achondroplasia	CT	77	2.590	Mild decrease in white matter volume Hypoplastic pons and cerebellum	Mild decrease in white matter volume
			C-MRI	105	3.440	Mild decrease in white matter volume Hypoplastic pons and cerebellum Prior small cerebellar haemorrhages	Mild decrease in white matter volume
2	38, 4 M	HIE	C-MRI	5	3.790	Multifocal restricted diffusion: cortex, periventricular white matter and deep grey structures	Restricted diffusion: corpus callosum and periventricular white matter
3	39, 2 F	Congenital heart defect	US	1	3.14	Normal	Normal
4	24, 0 F	Intraventricular haemorrhage	US	93	2.98	Stable prior right grade 3 and left grade 4 IVH	Prior left greater than right IVH likely left grade 4 and right grade 3 No new bleed
			US	99	3.030	Stable prior right grade 3 and left grade 4 IVH	Stable ventriculomegaly from prior IVH No new bleed
			C-MRI	108	3.350		Not Applicable Scan aborted due to motion
5	38, 2 M	Seizures and intracranial haemorrhage	C-MRI	5	3.928	Right temporal lobe and subpial haemorrhage	Right temporal lobe and subpial haemorrhage
6	40, 0 M	Congenital heart defect	C-MRI	4	2.990	Normal	Normal
7	28, 1 F	Intraventricular haemorrhage	US	88	2.735	Evolving bilateral intraventricular haemorrhage Stable ventriculomegaly	Prior left greater than right IVH likely left and right grade 3 No new bleed Right shunt in place
			US	95	2.94	Evolving bilateral intraventricular haemorrhage Stable ventriculomegaly	Similar hydrocephalus Right shunt in place
8	37, 0 M	Myelomeningocele	US	6	2.880	Mild prominence of the lateral and third ventricles and Chiari II Subsequent MRI demonstrated no Chiari*	Mild hydrocephalus No Chiari
9	40, 3 M	Congenital heart defect	C-MRI	2	3.5	Small foci of restricted diffusion: right periventricular white matter	Normal
10	37, 5 M	Congenital heart defect	C-MRI	3	2.7	Normal	Normal
11	38, 3 F	Transient tachypnoea of the newborn with possible seizures	C-MRI	3	3.485	Normal	Normal
12	39, 6 F	Neonatal stroke causing seizures	C-MRI	4	3.052	Multifocal restricted diffusion: left parietal and occipital lobes and smaller foci in the left periventricular white matter, basal ganglia and midbrain	Large area of restricted diffusion in left posterior frontal, parietal and occipital lobes
13	28, 0 M	Myofibromatosis	US, CT, C-MRI	122	4.235	Large right supratentorial brain tumour	Complex large right supratentorial haemorrhage
14	36, 0 F	HIE	C-MRI	4	2.00	Normal	Normal

Bold indicates major discrepancies between SOC imaging and portable MRI.
*Note that in patients 2, 5, 6 and 9–12 also had head ultrasounds during their hospital course, but these ultrasounds were not within 24 hours of the portable MRI examination.
C-MRI, conventional MRI; F, female; HIE, hypoxic ischaemic encephalopathy; IVH, intraventricular haemorrhage; M, male; SOC, standard of care; US, ultrasound.