Table 1

Concentrations of sex steroids in infant plasma and donor plasma units before transfusion start

Sex steroidDonor (n=19)All infants (n=19)Boys (n=7)Girls (n=12)P, boys vs girlsP, donor vs allP, donor vs boysP, donor vs girls
Progesterone (pg/mL)37.0 (37.0–37.0)901 (599–1774)1237 (901–1997)859 (599–1602)0.205<0.001n.t.n.t.
Dehydroepiandrosterone (pg/mL)1918 (1325–2408)4119 (2801–14 625)4912 (2801–14 625)4031 (1308–13 031)0.6720.002n.t.n.t.
Androstenedione (pg/mL)424 (303–534)842 (443–1684)957 (842–1969)599 (414–1189)0.1760.002n.t.n.t.
Testosterone (pg/mL)3394 (2671–4509)2668 (1650–11 495)29.2 (4.0–70.7)0.000n.t.0.565<0.001
Dihydrotestosterone (pg/mL)255 (208–361)188 (171–856)12.4 (6.7–30.5)0.001n.t.0.565<0.001
Oestrone (pg/mL)17.4 (10.4–20.1)3.1 (1.1–10.2)7.2 (2.5–10.2)2.4 (0.47–10.8)0.373<0.001n.t.n.t.
Oestradiol (pg/mL)16.0 (11.7–17.2)0.25 (0.25–2.55)0.25 (0.25–0.25)*0.021n.t.0.002<0.001
  • Concentrations are reported as medians (Q1–Q3). P, Mann–Whitney U-test.

  • *All measurements below the LLOQ.

  • LLOQ, lower limit of quantification; n.t., not tested.