Table 1

NIV support use on day of birth and rates of requiring escalation in respiratory support within 7 days in infants born at <32 weeks’ gestation from 2010 to 2017 in England and Wales

YearTotal admissions, nReceived HFNC as initial support* n (%)Received CPAP as initial support* n (%)
Total,
n (%)
Received CPAP and/or mechanical ventilation within 7 days,
n (%)
Received mechanical ventilation within 7 days,
n (%)
Total,
n (%)
Received mechanical ventilation within 7 days, n (%)
Infants born at <32 weeks’ gestational age
 2010647963 (1.0)16 (25.4)11 (17.5)1394 (21.5)203 (14.6)
 2011692997 (1.4)42 (43.3)17 (17.5)1660 (24.0)302 (18.2)
 20126981113 (1.6)49 (43.4)22 (19.5)1685 (24.1)298 (17.7)
 20137081183 (2.6)78 (42.6)36 (19.7)1730 (24.4)325 (18.8)
 20146963248 (3.6)102 (41.1)47 (19.0)1831 (26.3)354 (19.3)
 20157317356 (4.9)149 (41.9)67 (18.8)1950 (26.7)377 (19.3)
 20167377415 (5.6)146 (35.2)64 (15.4)1985 (26.9)374 (18.8)
 20177410521 (7.0)166 (31.9)83 (15.9)2077 (28.0)390 (18.8)
All56 5371996 (3.5)748 (37.5)347 (17.4)14 312 (25.3)2623 (18.3)
Subgroup of infants born at <28 weeks’ gestational age
 2010190912 (0.6)4 (33.3)3 (25.0)88 (4.6)26 (29.5)
 2011215021 (1.0)9 (42.9)6 (28.6)97 (4.5)28 (28.9)
 2012217119 (0.9)13 (68.4)7 (36.8)103 (4.7)34 (33.0)
 2013209216 (0.8)11 (68.8)7 (43.8)82 (3.9)27 (32.9)
 2014209222 (1.1)19 (86.4)14 (63.6)106 (5.1)45 (42.5)
 2015219939 (1.8)26 (66.7)14 (35.9)110 (5.0)36 (32.7)
 2016223244 (2.0)22 (50.0)11 (25.0)125 (5.6)36 (28.8)
 2017221656 (2.5)31 (55.4)22 (39.3)125 (5.6)31 (24.8)
All17 061229 (1.3)135 (59.0)84 (36.7)836 (4.9)263 (31.5)
Subgroup of infants born at 28–31 weeks’ gestational age
 2010457051 (1.1)12 (23.5)8 (15.7)1306 (28.6)177 (13.6)
 2011477976 (1.6)33 (43.4)11 (14.5)1563 (32.7)274 (17.5)
 2012481094 (2.0)36 (38.3)15 (16.0)1582 (32.9)264 (16.7)
 20134989167 (3.3)67 (40.1)29 (17.4)1648 (33.0)298 (18.1)
 20144871226 (4.6)83 (36.7)33 (14.6)1725 (35.4)309 (17.9)
 20155118317 (6.2)123 (38.8)53 (16.7)1840 (36.0)341 (18.5)
 20165145371 (7.2)124 (33.4)53 (14.3)1860 (36.2)338 (18.2)
 20175194465 (9.0)135 (29.0)61 (13.1)1952 (37.6)359 (18.4)
All39 4761767 (4.5)613 (34.7)263 (14.9)13 476 (34.1)2360 (17.5)
  • *Mode of respiratory support on day of birth.

  • CPAP, continuous positive airway pressure; HFNC, high flow nasal cannula oxygen; NIV, non-invasive ventilation.