Table 2

A comparison of HUI3 multi-attribute utility scores at 11 years of age for children born <26 weeks of gestation in England and term-born controls in 1995 (EPICure) and 2006 (EPICure2)

EPICure 1995EPICure2 2006Difference in means (95% CI) 2006 vs 1995
Mean (SD)Median (IQR)Mean (SD)Median (IQR)UnadjustedAdjusted*
EP children0.77 (0.28) (n=140)0.87 (0.70–0.97)0.65 (0.35) (n=88)0.76 (0.38–0.97)0.12 (−0.20 to –0.04)0.27 (−0.41 to –0.12)
EP children after excluding those with severe impairment0.83 (0.21) (n=122)0.91 (0.77–1.00)0.75 (0.28) (n=66)0.86 (0.65–0.97)0.08 (−0.15 to –0.01)0.14 (−0.26 to –0.01)
Controls0.96 (0.10) (n=141)1.00 (0.95–1.00)0.95 (0.12) (n=120)1.00 (0.93–1.00)−0.01 (−0.04 to 0.02)
  • Bold font indicates significant changes over time.

  • *Adjusted for significant differences between the two cohorts, including ethnicity (white, black, South Asian or other), maternal education (low, medium or high), maternal age at birth, any breast milk (yes or no), enteral feeding by day 7 (yes vs no), postnatal systemic steroids (yes vs no) and exact age at the 11-year assessment.

  • EP, extremely preterm; HUI, Health Utilities Index.