Incidence of HIE for the whole study population, infants ≥36 weeks gestational age with moderate/severe HIE and infants ≥36 weeks gestational age with moderate/severe HIE treated with TH
| Year | Any HIE | Moderate/severe HIE and ≥36 gestational weeks at birth | ||||||
| n | Rate per 1000 live births | n | Rate per 1000 live births | Received TH (n) | Received TH (%) | Received or died without TH (n) | Received or died without TH (%) | |
| 2011* | 2253 (2320–2372) | 3.22 (3.32–3.39) | 1592 (1631–1668) | 2.33 (2.33–2.39) | 694 (704–706) | 43.6 (42.3–43.2) | 722 (733–735) | 45.4 (43.9–45.1) |
| 2012 | 1916 | 2.71 | 1267 | 1.83 | 723 | 57.1 | 741 | 58.5 |
| 2013 | 1906 | 2.81 | 1213 | 1.83 | 806 | 66.4 | 823 | 67.8 |
| 2014 | 2135 | 3.17 | 1422 | 2.16 | 937 | 65.9 | 951 | 66.9 |
| 2015 | 2104 | 3.11 | 1396 | 2.11 | 928 | 66.5 | 953 | 68.3 |
| 2016 | 1881 | 2.77 | 1276 | 1.93 | 861 | 67.5 | 879 | 68.9 |
| Total | 12 195 | 2.96 | 8166 | 2.03 | 4949 | 60.6 | 5069 | 62.1 |
| Epoch 1* | 6075 (6142–6194) | 2.91 (2.94–2.96) | 4072 (4111–4138) | 2.00 (2.01–2.03) | 2223 (2233–2235) | 54.6† (54.0–54.4†) | 2286 (2297–2299) | 56.1† (55.5–55.9†) |
| Epoch 2 | 6120 | 3.01 | 4094 | 2.07 | 2726 | 66.6† | 2783 | 68.0† |
*Range included to account for 2011 data not available for all hospitals (see the Methods section).
†Significant change between epoch 1 and epoch 2 (p<0.001).
HIE, hypoxic-ischaemic encephalopathy; TH, therapeutic hypothermia.