Table 3

Infant characteristics at enrolment

Standard (n=29)
n (%)*
Restrictive (n=29)
n (%)*
Received respiratory support29 (100)29 (100)
 Supplemental oxygen25 (86)23 (79)
 CPAP3 (10)5 (17)
 Conventional ventilation24 (83)23 (79)
 High-frequency ventilation2 (7)2 (7)
Respiratory distress syndrome25 (86)27 (93)
 Surfactant first given in the delivery room17 (59)19 (66)
 Surfactant first given in the NICU10 (34)9 (31)
 Not given2 (7)1 (3)
Pneumothorax0 (0)2 (7)
Inhaled nitric oxide1 (3)2 (7)
Patien uctus rteriosu on echo5 (17)6 (21)
Indomethacin for prophylaxis0 (0)1 (3)
Indomethacin for PDA0 (0)0 (0)
Ibuprofen for PDA1 (3)0 (0)
Pulmonary haemorrhage1 (3)0 (0)
 Lowest recorded MABP (mm Hg), median (IQR)21.0 (20.0–23.0)22.0 (19.5–23.5)
Mean (SD) mm Hg BP<GA3.6 (2.1)3.5 (1.9)
Lactate (mmol/L), median (IQR)†1.9 (1.2–3.1)2.2 (1.6–4.6)
  • *Unless otherwise stated.

  • †n=27 in the standard group.

  • BP, blood pressure; CPAP, continuous positive airway pressure; GA, gestational age; MABP, mean arterial blood pressure ; NICU, neonatal intensive care unit; PDA, patent ductus arteriosus.