Table 2

Mean scores for IQ and academic attainment for the two EPICure cohorts at 11 years of births in England

EPICure 1995
22–25 weeks
EPICure2 2006
22–25 weeks
(c) versus (a)(a) versus (b)(c) versus (d)EPICure2 2006
22–26 weeks
(n=200)
EPICure (a)
(n=176)
Comparison (b)
(n=153)
EPICure2 (c)
(n=112)
Comparison (d)
(n=143)
Means
(95% CI)*
Adjusted
(95% CI)*†
Means (95% CI)*Adjusted (95% CI)*‡Means (95% CI)*Adjusted (95% CI)*‡
Mean (SD)Mean (SD)Mean (SD)Mean (SD)
Kaufmann ABC scores
Mental processing index (MPI)83 (18)
(n=174)
104 (11)
(n=153)
81 (19)
(n=112)
103 (12)
(n=143)
−1.3
(−5.8 to 3.2)
−0.7
(−5.0 to 3.6)
−21
(−25 to –18)§
−21
(−25 to –17)**
−22
(−26 to –18)§
−21
(−25 to –17)§
 85 (19)
 (n=200)
MPI z-score¶−1.9 (1.7)−1.8 (1.6)0.1 (−0.3 to 0.5)0.2
(−0.2 to 0.6)
−1.9
(−2.3 to –1.6)§
−1.9
(−2.2 to –1.6)§
−1.8
(−2.2 to –1.5)§
−1.8
(−2.1 to –1.4)§
 −1.5 (1.6)
 (n=200)
WIAT-II Composite Scores
Reading79 (21)
(n=171)
99 (12)
(n=153)
88 (22)
(n=108)
103 (11)
(n=140)
9.1 (3.9 to 14)**9.3 (4.2 to 14)§−19 (−23 to –16)§−18 (−22 to –14)§−15 (−19 to –11)§−14 (−19 to –10)§92 (21)
(n=195)
Reading z-score−1.6 (1.7)−1.3 (2.0)0.2 (−0.2 to 0.7)0.2 (−0.2 to 0.7)−1.6
(−1.9 to –1.3)§
−1.5
(−1.9 to –1.2)‡
−1.4
(−1.8 to –1.0)§
−1.3
(−1.7 to –0.9)§
−1.0 (1.9)
(n=195)
Mathematics70 (21)
(n=173)
99 (15)
(n=153)
83 (28)
(n=110)
109 (16)
(n=139)
13
(7.2 to 18)§
14
(7.9 to 19)§
−28
(−32 to –24)§
−27
(−32 to –23)§
−26
(−32 to –21)§
−25
(−31 to –20)§
87 (27)
(n=197)
Maths z-score−1.9 (1.4)−1.6 (1.7)0.3
(−0.1 to 0.7)
0.3
(−0.0 to 0.7)
−1.9
(−2.1 to –1.6)§
−1.8
(−2.1 to –1.5)§
−1.6
(−2.0 to –1.3)§
−1.6
(−1.9 to –1.2)§
−1.4 (1.7)
(n=197)
  • WIAT-II:Wechsler Inidividual Achievement Test - Second edition

  • *Difference in means.

  • †Multiple linear regression models were used to adjust for gestation, Birthweight z-score, male sex, multiple birth, maternal age and IMD at 11 years.

  • ‡Multiple linear regression models were used to adjust for male sex and IMD at 11 years.

  • §P<0.001.

  • ¶z-Scores calculated using control group scores as reference to adjust for temporal changes.

  • **P=0.001.

  • IMD, Index of Multiple Deprivation.