Table 2

Outcomes by feeding group: unmatched and matched cohorts

VariableUnmatched cohortMatched cohort
No parenteral nutritionParenteral nutritionNo parenteral nutritionParenteral nutrition
N3975187212401240
Blood culture positive late onset infection
 N (%)16 (0.4)14 (0.9)<5 (<0.5)11 (0.9)
Late onset infection (pragmatic definition)
 N (%)1175 (25.9)383 (26.0)313 (25.3)323 (26.1)
Severe NEC (confirmed at surgery, postmortem or recorded on death certificate)
 N6 (0.1)<5 (<0.5)7 (0.6)<5 (<0.5)
NEC (pragmatic definition)
 N (%)52 (1.1)16 (1.1)17 (1.4)13 (1.1)
Survival at discharge 
 N (%)4056 (89.5)1374 (93.2)1116 (90.0)1154 (93.1)
Hypoglycaemia
 N (%)946 (20.9)258 (17.5)235 (18.9)212 (17.1)
Onset of breast feeding (days)
 Median (IQR)7 (6–9)7 (6–9)7 (6–9)7 (6–9)
Breast feeding at discharge
 N (%)2110 (46.5)670 (45.4)582 (47.0)575 (46.4)
Time to first mother’s milk (days)
 Median (IQR)5 (4–6)5 (3–5)5 (4–6)5 (3–5)
Days with a central venous line in situ
 Median (IQR)5 (3, 6)5 (4, 7)5 (3, 6)5 (4, 7)
Weight Z-score at discharge
 Median (IQR)−0.6 (−1.4 to 0.2)−0.7 (−1.4 to 0.1)−0.7 (−1.4 to 0.1)−0.6 (−1.4 to 0.2)
Length of stay (days)
 Median (IQR)11 (8–17)10 (7–13)11 (8–16)11 (8–16)
  • N, number; NEC, necrotising enterocolitis.