Distribution of HbF, Hb and PaO2 during postnatal week 1 in relation to BPD
BPD | Unadjusted | Adjusted* | Adjusted† | ||||||
Postnatal week 1 | Yes | No | P value | OR by a 95% CI | P value | OR by a 95% CI | P value | OR by a 95% CI | |
HbF | Mean % (SD) | 61.8 (19.1) | 78.6 (14.7) | <0.001 | 0.55 (0.47 to 0.64)‡ | <0.001 | 0.63 (0.52 to 0.77)‡ | <0.001 | 0.64 (0.49 to 0.83)‡ |
Hb | Mean g/L (SD) | 146.3 (8.6) | 153.7 (11.3) | <0.001 | 0.44 (0.34 to 0.57)‡ | 0.002 | 0.62 (0.46 to 0.84)‡ | <0.001 | 0.36 (0.20 to 0.64)‡ |
PaO2 | Mean kPa (SD) | 7.4 (0.7) | 8.2 (1.3) | <0.001 | 0.47 (0.36 to 0.59) | <0.001 | 0.43 (0.30 to 0.60) | 0.004 | 0.45 (0.26 to 0.77) |
*Adjusted for gestational age at birth, birth weight small for gestational age, sex, highest and lowest FiO2 (12 hours).
†In the full statistical model, adjusted for gestational age at birth, birth weight small for gestational age, sex, highest and lowest FiO2 (12 hours) and CRIB-II score.
‡OR by a 10-unit increase p values <0.05 in bold.
BPD, bronchopulmonary dysplasia; CRIB, Clinical Risk Index for Babies scoring system II; FiO2, fractional inspired oxygen; Hb, haemoglobin; HbF, fetal haemoglobin; PaO2, partial oxygen pressure.