Perinatal and sociodemographic characteristics of the EP children assessed at 8 years of age
| No IVH n=331 (66%) | Grade of IVH* | P value† | ||||
| 1 n=80 (16%) | 2 n=53 (11%) | 3 n=23 (5%) | 4 n=12 (2%) | |||
| Perinatal variables | ||||||
| Antenatal corticosteroids | 279 (84%) | 60 (75%) | 39 (74%) | 14 (61%) | 8 (67%) | 0.001 |
| Multiple birth | 105 (32%) | 18 (22%) | 7 (13%) | 0 (0%) | 3 (25%) | <0.001 |
| GA at birth, weeks, mean (SD) | 25.8 (1.1) | 25.7 (1.2) | 25.5 (1.2) | 25.7 (1.2) | 25.5 (1.4) | 0.20‡ |
| Birth weight, g, mean (SD) | 865 (182) | 848 (192) | 848 (169) | 899 (190) | 853 (150) | 0.76‡ |
| Male | 164 (50%) | 39 (49%) | 26 (49%) | 16 (70%) | 10 (83%) | 0.032 |
| Surfactant | 221 (67%) | 53 (66%) | 37 (70%) | 17 (74%) | 7 (58%) | 0.80 |
| Indomethacin for PDA | 159 (48%) | 47 (59%) | 31 (58%) | 10 (43%) | 9 (75%) | 0.08 |
| Postnatal corticosteroids | 105 (32%) | 38 (48%) | 23 (43%) | 9 (39%) | 7 (58%) | 0.09 |
| Bronchopulmonary dysplasia | 146 (44%) | 48 (60%) | 27 (51%) | 12 (52%) | 9 (75%) | 0.016 |
| NEC | 26 (8%) | 4 (5%) | 3 (6%) | 3 (13%) | 3 (25%) | 0.23 |
| Cystic PVL | 11 (3%) | 5 (6%) | 2 (4%) | 3 (13%) | 3 (25%) | 0.001 |
| Surgery in newborn period | 93 (28%) | 23 (29%) | 17 (32%) | 9 (39%) | 7 (58%) | 0.037 |
| Sociodemographic variables | ||||||
| Mothers age at birth, years, mean (SD) | 29.7 (5.7) | 29.9 (5.6) | 29.6 (6.1) | 29.0 (7.3) | 26.9 (5.1) | 0.53‡ |
| Lower social class at 8 years | 104/320 (32%) | 23/78 (29%) | 14/51 (27%) | 11 (48%) | 7 (58%) | 0.17 |
| Lower maternal education | 155/329 (47%) | 38/78 (49%) | 28/52 (54%) | 15/22 (68%) | 6/11 (55%) | 0.08 |
Data are n (%), unless otherwise specified.
*According to Papile.3
†From χ2 trend unless otherwise stated.
‡From one-way ANOVA.
ANOVA, analysis of variance; EP, extremely preterm; GA, gestational age; IVH, intraventricular haemorrhage; NEC, necrotising enterocolitis; PDA, patent ductus arteriosus; PVL, periventricular leukomalacia.