Infant characteristics
| All infants | Treated by NICE | Treated by SRC | Untreated by 4 hours | |
| Total 70 | Total 39 | Total 27 | Total 31 | |
| n (%) | n (%) | n (%) | n (%) | |
| Gestation ≥34 to <37 weeks (n) | 9 (12.9%) | 6 (15.4%) | 4 (14.8%) | 3 (9.7%) |
| Maternal temperature ≥38°C (n) | 10 (14.3%) | 10 (25.6%) | 4 (14.8%) | 0 |
| Mean ROM (hours) | 23 | 29 | 24 | 15 |
| ROM ≥24 hours (n) | 24 (34.3%) | 19 (48.8%) | 9 (33.3%) | 6 (19.4%) |
| Maternal GBS (n) status by 4 hours | ||||
| Negative | 6 (8.6%) | 1 (2.6%) | 1 (3.7%) | 5 (16.1%) |
| Positive | 4 (5.7%) | 4 (10.3%) | 0 | 0 |
| Unknown | 60 (85.7%) | 34 (87.2%) | 26 (96.3%) | 26 (83.9%) |
| Intrapartum antibiotics (n) | ||||
| Broad spectrum >4 hours prior to birth | 2 (2.9%) | 2 (5.1%) | 0 | 0 |
| Broad spectrum 2–3.9 hours prior to birth | 6 (8.6%) | 6 (15.4%) | 2 (7.4%) | 0 |
| GBS specific >2 hours prior to birth | 4 (5.7%) | 4 (10.3%) | 2 (7.4%) | 0 |
| None or <2 hours prior to birth | 58 (82.9%) | 27 (69.2%) | 23 (85.2%) | 31 (100%) |
| ≥1 NICE red flag (n) | 29 (41.4%) | 29 (74.4%) | 25 (92.6%) | 0 |
| 1 NICE risk factor (n) | 30 (42.9%) | 19 (48.7%) | 17 (63%) | 11 (35.5%) |
| ≥2 NICE risk factors (n) | 18 (25.7%) | 18 (46.2%) | 8 (29.6%) | 0 |
| None of the above | 20 (28.6%) | 0 | 0 | 20 (64.5%) |
| Clinical illness category to 4 hours (n) | ||||
| Well | 43 (61.4%) | 13 (33.3%) | 1 (3.7%) | 30 (96.8%) |
| Equivocal | 1 (1.4%) | 0 | 0 | 1 (3.2%) |
| Unwell | 26 (37.2%) | 26 (66.7%) | 26 (96.3) | 0 |
| CRP in the first 4 hours | ||||
| Number of values | 41 (58.6%) | 38 (97.4%) | 26 (96.3) | 3 (9.7%) |
| Mean | 11.8 | 12.4 | 13 | 4 |
| Median (range) | 3 (0.1–64) | 3 (0.1–64) | 2.1 (0.1–64) | 3 (1–8) |
| CRP>10 (n) | 13 (18.6%) | 13 (33.3%) | 9 (33.3%) | 0() |
| Max CRP | ||||
| Number of values | 68 (97.1%) | 38 (97.4%) | 26 (96.3%) | 30 (96.8%) |
| Mean | 79.2 | 61.5 | 72 | 103.1 |
| Median (range) | 61.5 (3–300) | 52 (3–154) | 61.5 (10–154) | 85 (4–300) |
| CRP>10 (n) | 60 (85.7%) | 33 (84.6%) | 25 (92.6%) | 27 (87.1%) |
CRP, C-reactive protein; GBS, Group B Streptococcus; NICE, National Institute for Health and Care Excellence; ROM, rupture of membranes; SRC, sepsis risk calculator.