Table 3

Secondary outcomes

n (DRIFT:standard)DRIFT
n (%) or mean (SD)
Standard
n (%) or mean (SD)
Unadjusted difference
(95% CI), p value
Adjusted difference*
(95% CI), p value
Parent-reported visual function
Good vision27:2423 (85%)17 (71%)2.37 (0.60 to 9.40), 0.22†3.73 (0.66 to 21.14), 0.14†
Questionnaire mean score28:214.50 (0.70)4.65 (0.38)−0.15 (−0.49 to 0.19), 0.38‡−0.12 (−0.47 to 0.24), 0.50‡
Sensorimotor disability
None2 (7%)3 (14%)
Moderate27:212 (7%)2 (10%)0.55 (0.13 to 2.34), 0.42§3.66 (0.33 to 40.34), 0.29§
Severe23 (85%)16 (76%)
Cerebral palsy
Diagnosed with cerebral palsy (%)28:2417 (61%)14 (58%)1.10 (0.36 to 3.35), 0.86†0.37 (0.07 to 2.00), 0.25†
 GMFCS level 17 (41%)5 (36%)
 GMFCS level 24 (24%)3 (21%)
 GMFCS level 32 (12%)0 (0%)
 GMFCS level 40 (0%)2 (14%)
 GMFCS level 54 (24%)4 (29%)
Ambulant¶11 (65%)8 (57%)1.38 (0.32 to 5.88), 0.671.32 (0.24 to 7.25), 0.75
Strengths and Difficulties Questionnaire
Total score28:2214.89 (8.48)13.36 (6.59)1.53 (−2.89 to 5.94), 0.49‡2.01 (−2.78 to 6.81), 0.40‡
  • *Adjusted for age, sex, birth weight and grade of IVH.

  • †Logistic regression (OR).

  • ‡Linear regression (difference in means).

  • §Ordinal logistic regression (OR per increase in category).

  • ¶Children with cerebral palsy were categorised as ambulant (GMFCS level 1–2) or non-ambulant (GMFCS level 3–5).

  • DRIFT, drainage, irrigation and fibrinolytic therapy; GMFCS, Gross Motor Function Classification System; IVH, intraventricular haemorrhage.