Logistic regression analysis with different outcome variables: primary outcome, effective sedation and hypotension
| Primary outcome (n=89) | Effective sedation (n=83) | Hypotension (n=82) | |||||||
| OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
| Gestational age (weeks) | 0.94 | 0.77 to 1.15 | 0.54 | 1.00 | 0.80 to 1.23 | 0.98 | 1.09 | 0.94 to 1.26 | 0.26 |
| Birth weight <10th percentile (yes/no) | 0.85 | 0.22 to 3.34 | 0.82 | 1.07 | 0.27 to 4.27 | 0.93 | 1.55 | 0.52 to 4.25 | 0.47 |
| Male gender (yes/no) | 1.72 | 0.46 to 6.40 | 0.42 | 2.67 | 0.76 to 9.36 | 0.13 | 0.94 | 0.36 to 2.45 | 0.90 |
| Postnatal age (in hours) | 1.00 | 0.99 to 1.00 | 0.69 | 1.00 | 0.99 to 1.00 | 0.65 | 1.00 | 0.99 to 1.00 | 0.45 |
| Starting dose of propofol (mg/kg) | 4.50 | 0.92 to 22.11 | 0.06 | 57.04 | 7.58 to 429.49 | <0.001 | 1.09 | 0.35 to 3.39 | 0.88 |
| Cumulative dose of propofol (mg/kg) | 0.74 | 0.48 to 1.14 | 0.18 | ||||||
Corrected by Firth’s method to reduce bias because of relatively small sample size.