Closed loop (n=10) | Control (n=10) | P value | |
Time spent with sensor glucose level (%) | |||
4.0–8.0 mmol/L* | 91 (78-99) | 26 (6-64) | <0.001 |
2.6–10 mmol/L | 100 (94-100) | 84 (46-98) | 0.133 |
>10.0 mmol/L | 0 (0-6) | 16 (2-54) | 0.113 |
<2.6 mmol/L | 0.0 (0.0-0.0) | 0.0 (0.0-0.0) | 0.720 |
Baseline sensor glucose (mmol/L) | 7.9 (6.9-11.5) | 8.2 (7.0-12.4) | 0.182 |
Mean sensor glucose (mmol/L) | 6.2 (6.1-7.1) | 8.6 (7.4-11.1) | 0.002 |
SD of sensor glucose (mmol/L) | 1.0 (0.8-1.9) | 1.3 (0.9-2.5) | 0.604 |
Episodes of blood glucose <2.6 mmol/L† | 1 | 0 | 1.000 |
Insulin (U/kg/hour) | 0.04 (0.03-0.07) | 0.02 (0.00-0.11) | 0.400 |
Nutritional intake | |||
Dextrose (mg/kg/min) | 8.4 (7.2-10.3) | 8.5 (4.2-10.6) | 0.604 |
Protein (g/kg/day) | 3.2 (2.5-4.1) | 3.5 (1.6-4.1) | 1.000 |
Lipid (g/kg/day) | 1.8 (1.0-1.8) | 1.4 (0.9-2.2) | 0.905 |
Trophic feeds | 4 | 4 | 1.000 |