Comparison of antibiotic use as per NICE guidance vs recommendations of the SRC in the study population
| Kaiser Permanente SRC | Total (% of study cohort) | |||
| No antibiotics | Antibiotics | |||
| Current guidance (NICE) | No antibiotics | 3011 | 6 | 3017 (84) |
| Antibiotics | 426 | 150 | 576 (16) | |
| Total (% of study cohort) | 3437 (95.7) | 156 (4.3) | 3593 (100) | |
Sixteen per cent antibiotics as per NICE compared with 4.3% as per SRC. Absolute difference 11.7% (95% CI 10.64 to 12.74), p<0.0001, McNemar’s test for matched proportions.
NICE, National Institute for Health and Care Excellence; SRC, sepsis risk calculator.