Table 2

Comparison of clinical parameters between infants with and without IVH

IVH
(n=12 163)
No IVH
(n=43 038)
P valueOR (95% CI)
Mean maternal age (SD)28.5 (7.1)29.2 (6.7)<0.001
Maternal ethnicity (%)
 Indigenous*1455 (11.9)4786 (11.1)0.011.1 (1.0 to 1.1)
 Asian809 (6.7)2956 (6.9)0.41.0 (0.9 to 1.0)
 Caucasian8335 (68.5)30 078 (69.9)0.010.9 (0.9 to 1.0)
 Other200 (1.6)733 (1.7)0.71.0 (0.7 to 1.1)
Assisted conception (%)1223 (11.7)4658 (12.6)0.010.9 (0.9 to 1.0)
Multiple gestation (%)2924 (24.0)12 793 (29.7)<0.0010.8 (0.7 to 0.8)
Vaginal birth (%)6615 (54.7)14 681 (34.4)<0.0012.5 (2.0 to 2.5)
PROM >24 hours (%)2575 (22.8)8701 (21.5)<0.011.0 (1.0 to 1.1)
PIH (%)1354 (11.5)8128 (19.2)<0.0010.6 (0.5 to 0.6)
APH (%)2737 (23.5)9292 (22.2)<0.011.1 (1.0 to 1.1)
Antenatal steroids (%)9763 (83.0)36 627 (88.0)<0.0010.7 (0.6 to 0.7)
GA ≤27 weeks (%)6523 (53.6)11 555 (26.8)<0.0013.2 (3.0 to 3.3)
Mean GA, weeks (SD)27.2 (2.4)28.7 (2.1)<0.001
Mean birth weight, g (SD)1070 (374)1239 (373)<0.001
SGA (%)315 (2.6)1329 (3.1)<0.010.8 (0.7 to 0.9)
Outborn (%)2034 (17.2)4890 (11.5)<0.0011.7 (1.4 to 1.7)
Male (%)7042 (57.9)22 945 (53.4)<0.0011.3 (1.1 to 1.3)
Apgar score <7 at 5 min (%)3100 (25.5)5669 (13.2)<0.0012.5 (2.0 to 2.5)
Congenital anomalies (%)833 (7.1)2311 (5.5)<0.0011.3 (1.3 to 1.4)
Surfactant (%)8770 (72.5)21 892 (51.5)<0.0012.5 (2.0 to 2.5)
Survival (%)9876 (81.2)40 947 (95.1)<0.0010.2 (0.2 to 0.2)
Other major morbidities† (%)4194 (34.5)8386 (19.5)<0.0012.0 (2.0 to 2.5)
  • *Includes person of Aboriginal or Torres Strait Islander descent, Pacific Islander background or Maori.

  • †Having any one or more of: NEC stage 2 or higher, BPD, stage 3 or higher ROP, excluding severe IVH.

  • APH, antepartum haemorrhage; BPD, bronchopulmonary dysplasia; GA,  gestational age; IVH,  intraventricular haemorrhage; NEC, necrotising enterocolitis; PIH, pregnancy-induced hypertension; PROM, prolonged rupture of membrane; ROP, retinopathy of prematurity; SGA, small for gestational age.