Table 1

Patient characteristics

Characteristic	Entire study population (n=91)	Group 1 (n=18)	Group 2 (n=8)	Group 3 (n=25)	Group 4 (n=10)	Group 5 (n=26)	Group 6 (n=1)	Group 7 (n=2)	Group 8 (n=1)
Gestational age (week), median (IQR)	27.7 (25.9–30.6)	25.3 (24.8–25.6)	24.8 (24.4–25.6)	28.0 (26.9–28.9)	26.8 (26.3–27.1)	32.0 (30.4–33.6)	30.7	38.1	37.9
Birth weight (g), median (IQR)	1045 (825–1560)	720 (634–864)	740 (716–791)	1045 (890–1223)	938 (886–1076)	1678 (1480–2129)	1290	3845	2865
Birth weight <10th percentile, n (%)	23 (25)	5 (28)	0	8 (32)	1 (10)	8 (31)	1 (100)	0	0
Postnatal age (hour), median (IQR)	29 (9–213)	129 (38–173)	405 (384–681)	10 (6–31)	371 (307–524)	20 (5–26)	432	50	593
Actual weight (g), median (IQR)	1100 (830–1560)	705 (643–838)	923 (825–1084)	1065 (910–1193)	1105 (925–1123)	1678 (1460–2125)	1400	3848	3100
Male gender, n (%)	58 (64)	12 (67)	7 (88)	13 (52)	6 (60)	16 (62)	1 (100)	2 (100)	1 (100)
Reason for intubation, n (%)
RDS	44 (48.4)	2 (11.1)	0	17 (68)	0	23 (88.5)	0	2 (100)	0
Apnoea	19 (20.9)	9 (50)	5 (62.5)	2 (8)	3 (30)	0	0	0	0
Sepsis/NEC	11 (12.1)	5 (27.8)	1 (12.5)	3 (12)	1 (10)	1 (3.8)	0	0	0
Respiratory insufficiency	13 (14.3)	1 (5.6)	2 (25)	3 (12)	4 (40)	2 (7.7)	0	0	1 (100)
Elective*	2 (2.2)	0	0	0	1 (10)	0	1 (100)	0	0
Other	2 (2.2)	1 (5.6)	0	0	1 (10)	0	0	0	0
Propofol starting dose (mg/kg), n (%)
0.5	1 (1)	1 6)	0	0	0	0	0	0	0
1.0	30 (33)	4 (22)	5 (63)	5 (20)	6 (60)	6 (23)	1 (100)	2 (100)	1 (100)
1.5	23 (25)	5 (28)	3 (37)	5 (20)	4 (40)	6 (23)	0	0	0
1.75	9 (10)	0	0	5 (20)	0	4 15)	0	0	0
2.0	26 (29)	6 (33)	0	10 (40)	0	10 (38)	0	0	0
2.5	2 (2)	2 (11)	0	0	0	0	0	0	0