Table 2

Ventilation parameters, arterial blood gas status and cardiopulmonary physiology at fetal baseline and during the 120 min neonatal ventilation

Fetal60 min120 min
ICCPBCCp valueICCPBCCp valueICCPBCCp value
DLC (mL/cmH2O)0.6±0.10.5±0.10.230.7±0.20.6±0.10.32
FiO 2 0.6±0.20.8±0.10.340.5±0.20.7±0.10.21
Hb (g/L)119±7134±40.07123±8137±40.09131±10143±50.10
Hct (%)37±241±10.1138±242±10.0940±344±20.08
PaO 2 (mm Hg)21±225±10.3834±743±40.0934±740±40.36
SaO 2 (%)48±461±30.02*58±1476±70.1159±1473±100.30
PaCO 2 (mm Hg)64±266±30.9592±2195±150.9090±2895±160.92
pH7.26±0.027.24±0.010.797.10±0.107.12±0.060.857.11±0.157.09±0.070.85
Heart rate147±11144±60.95184±11168±70.23180±21171±80.38
PAP (mm Hg)47±352±40.3355±657±30.7055±558±20.33
Mean PBF (mL/min/kg)1±0.31.4±10.6912±529±50.01*8±223±40.01*
PBF/g lung weight0.3±0.10.6±0.30.813.5±1.55.2±0.60.341.8±0.54.0±0.40.04*
End-diastolic PBF−9±1−12±20.454±412±30.02*0.6±111±30.02*
PVR (mm Hg)/(L/min)6.1±0.75.2±0.70.251.7±0.60.5±0.1<0.01*2.2±0.60.6±0.1<0.01*
PVR×g lung weight123±24119±170.8930±911±2<0.01*37±815±2<0.01*
CAP (mm Hg)46±253±30.2456±760±30.4956±660±30.26
CBF (mL/min/kg)17±222±10.1618±320±40.9714±319±40.62
SctO(%)43±656±20.3250±1060±50.2355±1062±50.51
  • *p<0.05. Two-way repeated measures  analysis of variance (group, time) with post hoc analysis (Holm-Sidak) determining differences between groups at each timepoint.

  • CAP, carotid arterial pressure; ICC, immediate cord clamping; CBF, carotid arterial blood flow; DLC, dynamic lung compliance; FiO2, fraction of inspired oxygen; Hb, arterial haemoglobin concentration; Hct, haematocrit; PaCO2, partial pressure of arterial carbon dioxide; PaO2, partial pressure of arterial oxygen; PAP, pulmonary arterial pressure; PBCC, physiologically based cord clamping; PBF, pulmonary arterial blood flow; PVR, pulmonary vascular resistance; SaO2, arterial oxygen saturation; SctO2, cerebral tissue oxygen saturation.