Table 3

Adverse events in neonates with difficult intubation*

Adverse eventsNon-difficult intubation (n=1733)Difficult intubation (n=276)P valueRisk ratio (95% CI)OR (95% CI)
Any tracheal intubation adverse event, n (%)241 (14)122 (44)<0.0013.2 (2.7 to 3.8)4.9 (3.7 to 6.4)
Severe tracheal intubation adverse events, n (%)51 (3)36 (13)<0.0014.4 (2.9 to 6.6)4.9 (3.2 to 7.7)
Non-severe tracheal intubation adverse events, n (%)210 (12)104 (38)<0.0013.1 (2.6 to 3.8)4.4 (3.3 to 5.8)
Severe desaturation, n (%)†732 (42)207 (75)1.7 (1.5 to 1.9)4.1 (3.0 to 5.5)
  • *Severe desaturation was defined as a drop in SpO2 by >20% from highest SpO2 before intubation to lowest SpO2 during intubation attempt.

  • †Difficult intubation was defined as three or more failed intubation attempts by a non-resident provider.