Adverse events in neonates with difficult intubation*
| Adverse events | Non-difficult intubation (n=1733) | Difficult intubation (n=276) | P value | Risk ratio (95% CI) | OR (95% CI) |
| Any tracheal intubation adverse event, n (%) | 241 (14) | 122 (44) | <0.001 | 3.2 (2.7 to 3.8) | 4.9 (3.7 to 6.4) |
| Severe tracheal intubation adverse events, n (%) | 51 (3) | 36 (13) | <0.001 | 4.4 (2.9 to 6.6) | 4.9 (3.2 to 7.7) |
| Non-severe tracheal intubation adverse events, n (%) | 210 (12) | 104 (38) | <0.001 | 3.1 (2.6 to 3.8) | 4.4 (3.3 to 5.8) |
| Severe desaturation, n (%)† | 732 (42) | 207 (75) | <0.001 | 1.7 (1.5 to 1.9) | 4.1 (3.0 to 5.5) |
*Severe desaturation was defined as a drop in SpO2 by >20% from highest SpO2 before intubation to lowest SpO2 during intubation attempt.
†Difficult intubation was defined as three or more failed intubation attempts by a non-resident provider.