Table 1

Characteristics of neonates, n=214*

Median (IQR)*
Gestational age at delivery (weeks)40 (39–41)
Birth weight (g)3435 (3110–3803)
Sex: n (%)
 Male137 (64.0)
 Female77 (36.0)
Apgar score at 5 min (n=209)5 (3–8)
Requirement for EEG monitoring: n (%)
 HIE107 (50.0)
 Clinician request67 (31.3)
 Stroke7 (3.3)
 Infectious4 (1.9)
 Metabolic3 (1.4)
 Other26 (12.1)
Baby developed HIE: n (%)
 Yes141 (65.9)
 No73 (34.1)
Clinical Sarnat score at 24 hours (n=132): n (%)
 Mild51 (38.6)
 Moderate57 (43.2)
 Severe24 (18.2)
Therapeutic hypothermia: n (%)
 Cooled106 (49.5)
 Uncooled108 (50.5)
Final diagnosis: n (%)
 HIE grade
  Mild50 (23.4)
  Moderate†59 (27.6)
  Severe24 (11.2)
 Metabolic/genetic disorder‡20 (9.3)
 Stroke§18 (8.4)
 Suspected seizures—unconfirmed12 (5.6)
 Perinatal asphyxia without clinical encephalopathy7 (3.3)
 Sepsis/meningitis6 (2.8)
 Intracranial haemorrhage5 (2.3)
 Other¶13 (6.1)
  • *Unless otherwise stated.

  • †n=1 had meningitis also.

  • ‡n=1 had severe HIE also.

  • §n=2 had mild HIE and n=3 had moderate HIE also.

  • ¶n=3 for postnatal cardiorespiratory arrest (n=1 with mild HIE also, n=1 with severe HIE also); n=2  for   each of: neonatal drug withdrawal syndrome; respiratory distress; seizures of unknown origin; n=1 for each of: congenital anaemia; congenital  brain malformation; meconium aspiration syndrome; tracheo-oesphageal atresia and cystic periventricular leukomalacia  periventricular leukomalacia.

  • EEG, electroencephalography; HIE, hypoxic-ischaemic encephalopathy.