Oxygen saturation range compliance
| Category | Automated control | Manual control | P values* |
| Target SpO2range† | |||
| Episodes/hour (counts) | 41 (32–52) | 38 (32–46) | 0.0387 |
| Average episode duration (s) | 70 (49–99) | 48 (31–61) | <0.0001 |
| Per cent time in range (%) | 80 (70–87) | 49 (40–57) | <0.0001 |
| SpO2>95%‡ | |||
| Episodes/hour (counts) | 37 (30–46) | 18 (13–25) | <0.0001 |
| Average episode duration (s) | 12 (9.5–14) | 48 (34–68) | <0.0001 |
| Per cent time in range (%) | 12 (8.9–16) | 23 (15–41) | <0.0001 |
| SpO2>98%‡ | |||
| Episodes/hour (counts) | 4.5 (1.8–8.5) | 5.5 (1.9–14) | 0.572 (NS) |
| Average episode duration (s) | 6.4 (5.1–7.0) | 24 (20–32) | <0.0001 |
| Per cent time in range (%) | 0.68 (0.29–1.4) | 3.7 (1.2–9.9) | <0.0001 |
| SpO2<range | |||
| Episodes/hour (counts) | 27 (22–30) | 24 (21–26) | 0.082 (NS) |
| Average episode duration (s) | 17 (15–21) | 42 (29–50) | <0.0001 |
| Per cent time in range (%) | 12 (8.8–17) | 28 (17–36) | <0.0001 |
| SpO2<80% for ≥60 s | |||
| Total number of episodes§ | 0 (0–1.3) | 5 (2.8–14) | <0.0001 |
| Average episode duration (s)¶ | 0 (0–69) | 119 (97–148) | <0.0001 |
Data presented as median (IQR) for n=30.
↵*Statistical analysis comprised Wilcoxon signed-rank test.
↵†Target range defined as SpO2≥90% if FiO2=21% or SpO2 90%–95% if FiO2>21%.
↵‡Data for above range categories reported for FiO2>21%.
↵§The range (min-max) is (0–10) for automated and (1–38) for manual control.
↵¶The range (min-max) is (0–118) s for automated and (60–191.3) s for manual control.
NS, not significant.