Table 3

Long-term outcomes for those infants who developed HIE grade 2 or 3

nHIE grade 2HIE grade 3P value*
3132
Acid-base statuspH mean (95% CI)6.83
(6.64 to 7.13)
6.72
(6.57 to 7.02)
0.0004
Base deficit mean (95% CI)16.6
(11.47 to 21.73)
21.5
(16.65 to 26.35)
0.0002
Follow-upDied2 (6%)19 (59%)
Survivors with follow-up data27/29 (93%)12/13 (92%)
Cerebral palsyNo cerebral palsy22 (81%)2 (17%)
Hemiplegic12
Diplegic21
Quadriplegic15
Dystonic12
Mild (GMFCS criteria)22
Moderate (GMFCS criteria)13
Severe (GMFCS criteria)25
OutcomeCombined death/cerebral palsy outcome7/29 (24%)29/31 (94%)
  • Deaths do not include infants who died without a diagnosis of HIE.

  • *P value from Student’s t-test.

  • GMFCS, Gross Motor Function Classification System; HIE, hypoxic-ischaemic encephalopathy.