Child demographics, clinical characteristics and neurological function at 6–7 years by trial arm, for surviving children in the UK with questionnaire data. Also shown are parental socioeconomic characteristics
| Control group (n=63) | Hypothermia group (n=67) | P values | |
| Baseline demographics and characteristics at trial entry | |||
| Male sex, n (%): | 34 (54) | 42 (63) | 0.31 |
| Missing | 0 | 0 | |
| Age (years) | |||
| Median (IQR) | 6.2 (6.1–6.5) | 6.3 (6.1–6.9) | 0.37 |
| Missing | 3 | 1 | |
| Gestational age (weeks): | |||
| Median (IQR) | 40 (39-41) | 40.3 (39.3–41.4) | 0.33 |
| Missing | 4 | 0 | |
| Birth weight (g): | |||
| Median (IQR) | 3400 (3194–3930) | 3450 (3175–3838) | 0.81 |
| Missing | 0 | 0 | |
| Delivery complications, n (%): | 46 (74) | 51 (76) | 0.80 |
| Missing | 1 | 0 | |
| Apgar score≤5 at 10 min, n (%): | 38 (72) | 39 (72) | 0.95 |
| Missing | 10 | 13 | |
| Outcomes at 6–7 years | |||
| Normal neurological function, n (%) | 31 (49) | 46 (69) | 0.02 |
| Missing | 0 | 0 | |
| IQ≥85, n (%) | 40 (67) | 54 (81) | 0.07 |
| Missing | 3 | 0 | |
| Overall disability*, n (%): | |||
| None | 27 (43) | 49 (75) | <0.001 |
| Mild | 10 (16) | 4 (6) | |
| Moderate | 8 (13) | 4 (6) | |
| Severe | 18 (29) | 8 (12) | |
| Missing | 0 | 2 | |
| Parental socioeconomic characteristics at 6–7 years | |||
| Main carer highest qualification, n (%): | 0.81 | ||
| None of the below | 2 (3) | 5 (7) | |
| Vocational qualification NVQ or CSE | 9 (15) | 9 (13) | |
| O Level, GCSE or Scottish Standards | 14 (23) | 11 (16) | |
| BTEC, A Levels or Scottish Highers | 6 (10) | 6 (9) | |
| Diploma or HND | 6 (10) | 11 (16) | |
| University degree | 12 (20) | 15 (22) | |
| Postgraduate university degree | 10 (16) | 9 (13) | |
| Other qualification | 2 (3) | 1 (1) | |
| Missing | 2 | 0 | |
| Main carer employment, n (%): | 0.02 | ||
| Employed | 22 (36) | 41 (61) | |
| Self-employed | 7 (11) | 2 (3) | |
| Unemployed | 14 (23) | 10 (15) | |
| Other† | 18 (30) | 14 (21) | |
| Missing | 2 | 0 | |
| Main carer home, n (%): | 0.89 | ||
| Owner (mortgage) | 40 (63) | 43 (64) | |
| Council rented | 11 (17) | 7 (10) | |
| Private rented (furnished) | 3 (5) | 2 (3) | |
| Private rented (unfurnished) | 3 (5) | 11 (16) | |
| Housing society or co-operative | 3 (5) | 1 (1) | |
| Other‡ | 3 (5) | 3 (4) | |
| Missing | 0 | 0 | |
*Overall disability—mild disability (an IQ score of 70–84, level 1 gross motor function (is able to walk independently but may have some gait abnormalities), or abnormality in one or both eyes with normal or nearly normal vision); moderate disability—(an IQ score of 55–69, level 2 or 3 gross motor function (has minimal ability to perform gross motor skills or requires assistance with walking), or moderately reduced vision); severe disability (an IQ score of <55, level 4 or 5 gross motor function (needs adaptive seating or has severely limited mobility), or no useful vision).
†Open-ended question (responses included housewife, carer, etc).
‡Open-ended question.
A Level, advanced level; BTEC, Business and Technology Education Council; CSE, Certificate of Secondary Education; HND, Higher National Diploma; O Level, ordinary level; GCSE, General Certificate of Secondary Education; IQR, Inter-quartile range; NVQ, National Vocational Qualification.