Infants in England with conditions leading to brain injury at or soon after birth
| Condition | Year | ||||
| 2012 | 2013 | 2014 | 2015 | ||
| Seizures | Number of cases | 1445 | 1432 | 1360 | 1249 |
| Rate per 1000 live births (95% CI) | 2.1 (2.0 to 2.1) | 2.2 (2.1 to 2.3) | 2.1 (2.0 to 2.2) | 1.9 (1.8 to 2.0) | |
| Number of term cases | 1065 | 1036 | 1009 | 919 | |
| Number of preterm cases | 378 | 396 | 351 | 330 | |
| Intracranial haemorrhage | Number of cases | 754 | 677 | 689 | 726 |
| Rate per 1000 live births (95% CI) | 1.1 (1.0 to 1.2) | 1.0 (0.9 to 1.1) | 1.0 (1.0 to 1.1) | 1.1 (1.0 to 1.2) | |
| Number of term cases | 110 | 94 | 104 | 117 | |
| Rate per 10 000 term births (95% CI) | 1.7 (1.4 to 2.1) | 1.5 (1.3 to 1.9) | 1.7 (1.4 to 2.1) | 1.9 (1.6 to 2.3) | |
| Number of preterm cases | 644 | 583 | 585 | 609 | |
| Severe P/IVH <32 weeks gestation | 483 | 445 | 468 | 452 | |
| Rate of severe P/IVH per 1000 live births <32 weeks (95% CI) | 60.4 (55.2 to 66.0) | 57.7 (52.6 to 63.4) | 61.1 (55.8 to 66.9) | 58.3 (53.1 to 63.9) | |
| Perinatal/neonatal stroke | Number of cases | 77 | 100 | 88 | 90 |
| Rate per 1000 live births (95% CI) | 0.11 (0.09 to 0.14) | 0.15 (0.12 to 0.18) | 0.13 (0.11 to 0.16) | 0.14 (0.11 to 0.17) | |
| Number of term cases | 64 | 78 | 72 | 76 | |
| Number of preterm cases | 13 | 22 | 16 | 14 | |
| Hypoxic-ischaemic encephalopathy | Number of cases | 1674 | 1674 | 1824 | 1742 |
| Rate per 1000 live births (95% CI) | 2.4 (2.3 to 2.5) | 2.5 (2.4 to 2.6) | 2.8 (2.6 to 2.9) | 2.6 (2.5 to 2.8) | |
| Number of term cases | 1409 | 1401 | 1480 | 1417 | |
| Number of preterm cases | 265 | 273 | 344 | 325 | |
| Central nervous system infection | Number of cases | 353 | 422 | 504 | 465 |
| Rate per 1000 live births (95% CI) | 0.51 (0.46 to 0.56) | 0.64 (0.58 to 0.70) | 0.76 (0.70 to 0.83) | 0.70 (0.64 to 0.77) | |
| Number of term cases | 188 | 266 | 284 | 277 | |
| Number of preterm cases | 165 | 156 | 220 | 188 | |
| Bilirubin encephalopathy | Number of cases | 8 | 7 | 2 | 4 |
| Rate per 100 000 live births (95% CI) | 1.2 (0.6 to 2.3) | 1.1 (0.5 to 2.2) | 0.3 (0.1 to 1.2) | 0.6 (0.2 to 1.6) | |
| Number of term cases | 6 | 5 | 2 | 4 | |
| Number of preterm cases | 2 | 2 | 0 | 0 | |
| Cystic periventricular leucomalacia | Number of preterm cases | 199 | 175 | 171 | 184 |
| Rate per 1000 live births (95% CI) | 0.3 (0.3 to 0.3) | 0.3 (0.2 to 0.3) | 0.3 (0.2 to 0.3) | 0.3 (0.2 to 0.3) | |
| Number of cases at <34 weeks gestation | 186 | 175 | 157 | 176 | |
| Rate per 1000 live births <34 weeks gestation (95% CI) | 12.7 (11.0 to 14.7) | 12.5 (10.7 to 14.4) | 11.3 (9.7 to 13.3) | 12.4 (10.7 to 14.4) | |
Infants can be diagnosed with more than one condition so the sum of conditions for each year will not match data given in tables 1–3; P/IVH, periventricular/intraventricular haemorrhage.