Simple gastroschisis (n=51) | Complex gastroschisis* (n=10) | p Value | |
Postnatal characteristics | |||
Eviscerated organs† | |||
- Intestines only | 21 (41%) | 3 (30%) | 0.73 |
- + stomach | 25 (49%) | 5 (50%) | 1.00 |
- + bladder | 6 (12%) | 2 (20%) | 0.61 |
Multiple congenital anomalies‡ | 7 (14%) | 2 (20%) | 0.63 |
Primary closure, directly after birth | 35 (69%) | 4 (40%) | 0.15 |
Procedures under general anaesthesia | 2 (1–3) | 7 (4–14) | <0.001 |
Duration of initial mechanical ventilation (days)§ | 2 (1–6) | 24 (7–30) | 0.001 |
Time to full enteral feeding (days) | 27 (20–47) | 165 (66–624) | <0.001 |
- Intestinal failure | 13 (25%) | 10 (100%) | <0.001 |
Length of initial hospital stay (days) | 42 (28–62) | 173 (81–426) | <0.001 |
Complications† | 30 (59%) | 10 (100%) | 0.01 |
- Sepsis | 25 (49%) | 9 (90%) | 0.03 |
- Parenteral nutrition-related cholestasis | 14 (27%) | 9 (90%) | <0.001 |
- Cardiopulmonary resuscitation | 5 (10%) | 1 (10%) | 1.00 |
- Central venous line-thrombosis | 2 (4%) | 2 (20%) | 0.12 |
- Miscellaneous¶ | 13 (25%) | 5 (50%) | 0.14 |
Data presented as median (IQR) or n (%).
*Bowel atresia (n=3), intestinal atresia+necrosis (n=2), intestinal atresia+perforation (n=1), necrosis (n=1), necrosis+volvulus (n=1), perforation (n=2).
†Percentages do not necessarily add up to 100, as one patient can have multiple problems.
‡Polydactyly (n=2); dysmorphic features (n=2: retrognathia and short philtrum, frontal bossing and hypertelorism); hydronephrosis and atrial septal defect, spontaneous closure (n=1); small ventricular septal defect (n=1); benign peripheral hydrocephalus (n=1); hypospadias (n=1); and retrognathia and urethral valves (n=1).
§Data unknown in n=1.
¶Surgery-related (n=8); preterm birth-related (n=4); infectious, not catheter-related (n=6); neurological (n=4); catheter-related (n=2); drug-related (n=1).