Table 1

Patient demographics

CHX–IA
(n=148)
PI
(n=156)
p Value
Gestational age (weeks)*27 (2)27 (2)0.558
Birth weight (g)*1017 (289)1014 (326)0.92
Male†81 (55)69 (44)0.067
Antenatal steroid exposure†144 (97)155 (99)0.309
Caesarean section†91 (61)100 (64)0.891
Clinical chorioamnionitis†14 (9)24 (15)0.082
Multiple birth†62 (42)54 (35)0.509
Apgar score at 1 min*6 (2)6 (2)0.537
Apgar score at 5 min*8 (2)8 (2)0.364
Ventilation prerandomisation†64 (43)78 (50)0.143
CPAP prerandomisation†102 (69)100 (64)0.221
UVC as first CVC†96 (65)104 (67)0.809
Day of life randomised‡
  • UVC first inserted (CHX 96, PI 104)

  • PICC first inserted (CHX–IA 52, PI 52)

0 (0, 1)
0 (0, 0)
1 (0, 1)
0 (0, 0)
0 (0, 0)
1 (0, 1)
0.438
Total CVCs3844310.328
Total CVC days146516130.400
No of CVCs per patient†3 (1)3 (1)0.121
Duration CVC in situ per patient (days)‡9 (6, 12)9 (6, 13)0.553
  • Data are * mean (SD), †n (%),  and ‡ median (IQR).

  • CHX–IA, 2% chlorhexidine–70% isopropyl alcohol; CPAP, continuous positive airway pressure; CVC, central venous catheter; PI, 10% aqueous povidone-iodine; UVC, umbilical venous catheter.