CHX–IA (n=148) | PI (n=156) | p Value | |
Gestational age (weeks)* | 27 (2) | 27 (2) | 0.558 |
Birth weight (g)* | 1017 (289) | 1014 (326) | 0.92 |
Male† | 81 (55) | 69 (44) | 0.067 |
Antenatal steroid exposure† | 144 (97) | 155 (99) | 0.309 |
Caesarean section† | 91 (61) | 100 (64) | 0.891 |
Clinical chorioamnionitis† | 14 (9) | 24 (15) | 0.082 |
Multiple birth† | 62 (42) | 54 (35) | 0.509 |
Apgar score at 1 min* | 6 (2) | 6 (2) | 0.537 |
Apgar score at 5 min* | 8 (2) | 8 (2) | 0.364 |
Ventilation prerandomisation† | 64 (43) | 78 (50) | 0.143 |
CPAP prerandomisation† | 102 (69) | 100 (64) | 0.221 |
UVC as first CVC† | 96 (65) | 104 (67) | 0.809 |
Day of life randomised‡
| 0 (0, 1) 0 (0, 0) 1 (0, 1) | 0 (0, 0) 0 (0, 0) 1 (0, 1) | 0.438 |
Total CVCs | 384 | 431 | 0.328 |
Total CVC days | 1465 | 1613 | 0.400 |
No of CVCs per patient† | 3 (1) | 3 (1) | 0.121 |
Duration CVC in situ per patient (days)‡ | 9 (6, 12) | 9 (6, 13) | 0.553 |
Data are * mean (SD), †n (%), and ‡ median (IQR).
CHX–IA, 2% chlorhexidine–70% isopropyl alcohol; CPAP, continuous positive airway pressure; CVC, central venous catheter; PI, 10% aqueous povidone-iodine; UVC, umbilical venous catheter.