Baseline characteristic* | Infants lost to follow-up n (%) n=28 | Infants with 1-year follow-up n (%) n=208 | p Value | |
Ethnicity | White British | 11 (42%) | 114 (59%) | 0.10 |
Other | 15 (58%) | 78 (41%) | ||
Sex | Male | 16 (57%) | 129 (62%) | 0.62 |
Female | 12 (43%) | 79 (38%) | ||
Median (IQR) gestational age at birth (completed weeks) | 27 (26–33) | 26 (25–30) | 0.12 | |
Median (IQR) birth weight (grams) | 1013 (657–1165) | 907 (720–1310) | 0.15 | |
Small for gestational age (<10th centile) | Yes | 6 (22%) | 30 (15%) | 0.30 |
No | 21 (78%) | 176 (85%) | ||
Ligation of PDA | Yes | 3 (11%) | 15 (7%) | 0.48 |
No | 24 (89%) | 192 (93%) | ||
Non-cardiac congenital anomaly | Yes | 3 (11%) | 23 (11%) | 1.00 |
No | 24 (89%) | 184 (89%) | ||
Abdominal wall erythema or discolouration at presentation | Yes | 7 (25%) | 65 (31%) | 0.5 |
No | 21 (75%) | 143 (69%) | ||
Operative diagnosis of SIP† | Yes | 0 (0%) | 32 (16%) | 0.02 |
No | 27 (100%) | 162 (84%) | ||
Surgical procedure | Resection and primary anastomosis | 5 (19%) | 35 (17%) | 0.83 |
Resection and stoma formation | 16 (62%) | 105 (51%) | ||
Stoma without resection | 4 (15%) | 34 (16%) | ||
Clip and drop with resection | 1 (4%) | 9 (4%) | ||
Open and close laparotomy | 0 | 10 (5%) | ||
Negative laparotomy | 0 | 2 (1%) | ||
Drain only | 0 | 6 (3%) | ||
No surgical intervention | 0 | 6 (3%) |
*Complete data were not obtained for all characteristics for all infants, and therefore numbers and percentages presented, including for surgical procedure, are based on the number of infants with data returned for that characteristic.
†Diagnosis was not possible for 12 infants who did not undergo laparotomy and was unknown in three despite undergoing a laparotomy.
PDA, patent ductus arteriosis, SIP, spontaneous intestinal perforation