Table 1

Classification of symptomatic congenital CMV infection

SymptomCriterion
Petechiae
Hepatosplenomegaly
Elevated liver enzymes>2 times the upper limit for both alanine aminotransferase and aspartate aminotransferase levels
Direct hyperbilirubinaemia>20% of total bilirubin level
Thrombocytopaenia<150 000/µL
Abnormal brain ultrasound imagingIntracranial calcifications, multiple germinal matrix cysts, LSV
MicrocephalyHead circumference less than the third percentile for the gestational age
SGAWeight less than the tenth percentile for the gestational age
Chorioretinitis
  • CMV, cytomegalovirus; LSV, lenticulostriate vasculopathy; SGA, small for gestational age.