Classification of symptomatic congenital CMV infection
Symptom | Criterion |
Petechiae | |
Hepatosplenomegaly | |
Elevated liver enzymes | >2 times the upper limit for both alanine aminotransferase and aspartate aminotransferase levels |
Direct hyperbilirubinaemia | >20% of total bilirubin level |
Thrombocytopaenia | <150 000/µL |
Abnormal brain ultrasound imaging | Intracranial calcifications, multiple germinal matrix cysts, LSV |
Microcephaly | Head circumference less than the third percentile for the gestational age |
SGA | Weight less than the tenth percentile for the gestational age |
Chorioretinitis |
CMV, cytomegalovirus; LSV, lenticulostriate vasculopathy; SGA, small for gestational age.