Table 3

Comparison of direct cost categories by presence of bronchopulmonary dysplasia, in 2014 US$, N=254

VariableWith BPD
N=77
Median (IQR)
Without BPD
N=177
Median (IQR)
p Value
Total NICU costs, hospital and physician269 004 (204 606–331 552)117 078 (90 496–162 017)<0.001
Hospital costs (direct+indirect)230 153 (185 540–290 469)107 749 (80 083–144 645)<0.001
Hospital direct costs144 588 (117 030–185 695)68 823 (51 109–92 009)<0.001
 NICU room and board115 580 (92 976–141 959)59 620 (43 416–78 231)<0.001
 Respiratory care11 662 (7935–17 214)1460 (365–4043)<0.001
 Pharmacy7983 (6225–12 059)3731 (2294–4983)<0.001
 Laboratory and pathology5349 (4247–7451)2200 (1406–2954)<0.001
 Diagnostic testing2284 (1730–3373)819 (521–1360)<0.001
 Surgery912 (0–1843)0 (0–902)<0.001
 Cardiology and echocardiography1005 (493–1645)238 (0–627)<0.001
 Therapy services (speech, physical, occupational)572 (379–909)311 (246–419)<0.001
 Psychology230 (148–280)230 (148–280)0.312
 Hospital indirect costs85 564 (65 651–106 107)40 096 (30 020–52 423)<0.001
Physician costs26 046 (19 067–40 187)10 018 (6228–15 592)<0.001
 Neonatology21 323 (16 208–34 037)8466 (5400–12 797)<0.001
 Cardiology331 (208–518)80 (0–182)<0.001
 Paediatric surgery312 (0–936)0 (0–670)<0.001
 Paediatric subspecialties155 (0–291)0 (0–0)<0.001
 Other surgeries426 (229–1250)142 (101–324)<0.001
Total NICU costs, hospital and physician, per day2445 (2243–2623)2195 (2064–2352)<0.001
 Hospital cost per day2179 (2017–2282)1994 (1877–2102)<0.001
 Physician cost per day217 (185–363)173 (135–246)<0.001
  • Analyses performed using Mann-Whitney U tests.

  • BPD, bronchopulmonary dysplasia; IQR, IQR, 25 percentile–75 percentile; NICU, neonatal intensive care unit.