Multivariable logistic regression of variables of all IVH and severe IVH
Outcome: IVH vs no IVH | Outcome: severe IVH vs other (no/mild IVH) | |||
---|---|---|---|---|
OR (95% CI) | p Value | OR (95% CI) | p Value | |
Birth-weight group (≥2500 g) | Reference | Reference | ||
Extremely low (<1000) | 29.27 (25.71 to 33.32) | <0.001 | 120.45 (75.67 to 191.74) | <0.001 |
Very low (1000–1499) | 16.56 (14.54 to 18.86) | <0.001 | 38.60 (24.20 to 61.57) | <0.001 |
Low (1500–2499) | 5.24 (4.60 to 5.98) | <0.001 | 6.60 (4.09 to 10.63) | <0.001 |
Missing BW data | 5.95 (5.21 to 6.80) | <0.001 | 23.18 (14.50 to 37.06) | <0.001 |
Female vs male | 0.85 (0.82–0.88) | <0.001 | 0.76 (0.72 to 0.80) | <0.001 |
Ethnicity (Caucasian) | Reference | Reference | ||
African–American | 1.15 (1.10 to 1.20) | <0.001 | 1.06 (0.97 to 1.15) | 0.191 |
Hispanic | 0.97 (0.93 to 1.02) | 0.209 | 1.08 (1.00 to 1.18) | 0.056 |
Asian/Pacific Islander | 1.01 (0.91 to 1.13) | 0.802 | 0.76 (0.61 to 0.94) | 0.013 |
Other including missing information | 1.05 (1.01 to 1.10) | 0.007 | 1.18 (1.10 to 1.26) | <0.001 |
Transport | 1.78 (1.71 to 1.86) | <0.001 | 1.94 (1.80 to 2.09) | <0.001 |
Trisomy 21 | 0.45 (0.30 to 0.69) | <0.001 | 0.38 (0.16 to 0.93) | 0.034 |
IDM | 0.62 (0.54 to 0.71) | <0.001 | 0.56 (0.42 to 0.74) | <0.001 |
Maternal hypertension | 0.62 (0.53 to 0.72) | <0.001 | 0.28 (0.18 to 0.43) | <0.001 |
Polycythaemia | 0.67 (0.49 to 0.92) | 0.013 | 0.79 (0.43 to 1.45) | 0.449 |
Caesarean birth | 0.79 (0.74 to 0.85) | <0.001 | 0.83 (0.73 to 0.94) | 0.004 |
Hypothermia | 0.86 (0.75 to 0.99) | 0.039 | 1.01 (0.81 to 1.28) | 0.903 |
PDA | 1.45 (1.40 to 1.50) | <0.001 | 1.38 (1.30 to 1.46) | <0.001 |
Neonatal sepsis | 1.55 (1.50 to 1.61) | <0.001 | 1.97 (1.86 to 2.08) | <0.001 |
Chest tube insertion | 1.38 (1.28 to 1.49) | <0.001 | 1.65 (1.46 to 1.85) | <0.001 |
Endotracheal intubation | 1.42 (1.37 to 1.47) | <0.001 | 1.27 (1.18 to 1.36) | <0.001 |
UV catheterisation | 1.18 (1.14 to 1.22) | <0.001 | 1.19 (1.12 to 1.26) | <0.001 |
Twin pregnancy | 1.18 (1.11 to 1.26) | <0.001 | 1.26 (1.12 to 1.42) | <0.001 |
BW, birth weight; IDM, infant of diabetic mother; IVH, intraventricular haemorrhage; PDA, patent ductus arteriosus; UV, umbilical venous.