Table 3

Postnatal predictors of retinopathy of prematurity (stages 3–5) in Swedish extremely preterm infants (n=489)

PeriodOR95% CI
Weight ΔSDS0–28 days0.790.59 to 1.07
Weight ΔSDS8–28 days0.780.59 to 1.03
Weight ΔSDS (GA >23 weeks)8–28 days0.75*0.57 to 0.99
CRIB score (one step increment)Any1.000.93 to 1.09
Mechanical ventilation† (days)0–28 days1.19**1.08 to 1.33
Postnatal steroids (days)0–28 days1.191.00 to 1.41
Antibiotic treatment (days)0–28 days1.161.00 to 1.35
Blood transfusion‡ (mL/day)0–28 days1.23**1.09 to 1.39
PDA treatment (any)Any1.95**1.26 to 3.02
PDA surgeryAny2.28***1.46 to 3.55
IVH any§ (grade 1–4)Any1.57**1.04 to 2.36
IVH§ grade 3–4Any2.13**1.12 to 4.03
Enteral fluids¶ (mL/kg/day)0–28 days0.85***0.78 to 0.93
Hospital0.980.95 to 1.01
  • Logistic regression analysis.

  • Adjusted for gestational age and birth weight.

  • *p<0.05; **p<0.01; ***p<0.001.

  • †One day per week increment.

  • ‡10 mL/kg per week increment.

  • §One grade increment.

  • ¶Enteral fluids (proportion of total fluids): 10% increment.

  • ΔSDS, delta SD score; CRIB, clinical risk index for babies; GA, gestational age; IVH, intraventricular haemorrhage; PDA, patent ductus arteriosus.