Outcome | Flow driver (n=25) | Bubble (n=28) | Effect* | 95% CI | ||
---|---|---|---|---|---|---|

CPAP days, GM† | 0.82 | 0.55 to 1.24 | 1.46 | 1.00 to 2.13 | 1.6 | 1.0 to 2.8 |

CPAP plus supplementary oxygen days, GM† | 3.12 | 1.92 to 5.07 | 5.25 | 3.27 to 8.45 | 1.6 | 0.9 to 2.9 |

Necrotising enterocolitis, n % | 1 | 4% | 0 | 0% | – | |

Retinopathy of prematurity, n % | 0 | 0% | 0 | 0% | – | |

Periventricular leucomalacia, n % | 0 | 0% | 2 | 7% | – | |

Periventricular haemorrhage, n % | 2 | 8% | 5 | 18% | 2.3 | 0.4 to 14 |

Death, n % | 1 | 4% | 3 | 11% | 2.3 | 0.2 to 28 |

Ventilation, n % | 2 | 8% | 6 | 21% | 2.9 | 0.5 to 17 |

Nasal excoriation, n % | 1 | 4% | 3 | 11% | 2.7 | 0.3 to 28 |

Pneumothorax, n % | 1 | 4% | 3 | 11% | 2.6 | 0.2 to 27 |

*ORs for binary outcomes, adjusted for gestational age; ratio for log transformed continuous outcomes, adjusted for gestational age, sex, antenatal steroids.

†GM and 95% CI, for survivors.

CPAP, continuous positive airway pressure; GM, geometric mean.