Multivariate logistic regression models predicting intraventricular haemorrhage (IVH), bronchopulmonary dysplasia (BPD) and death as dependent variables
| Independent variable | Dependent variable | ||
|---|---|---|---|
| IVH | BPD | Death | |
| Gestational age (week) | 0.76 (0.72 to 0.80) <0.001 | 0.71 (0.67 to 0.75) <0.001 | 0.69 (0.62 to 0.77) <0.001 |
| Female gender | 0.86 (0.72 to 1.03) 0.100 | 0.61 (0.51 to 0.75) <0.001 | 0.64 (0.44 to 0.94) 0.022 |
| Multiple birth | 1.28 (1.05 to 1.55) 0.013 | 0.75 (0.60 to 0.93) 0.008 | 1.32 (0.88 to 1.97) 0.177 |
| Small for gestational age (<10th percentile) | 0.65 (0.47 to 0.88) 0.006 | 2.59 (2.00 to 3.37) <0.001 | 2.86 (1.80 to 4.55) <0.001 |
| Maternal steroid treatment | 0.64 (0.47 to 0.87) 0.004 | 1.13 (0.80 to 1.60) 0.488 | 0.68 (0.38 to 1.24) 0.206 |
| Maternal treatment with antibiotics | 0.86 (0.69 to 1.06) 0.160 | 0.88 (0.70 to 1.11) 0.266 | 1.07 (0.68 to 1.69) 0.779 |
| Maternal treatment with tocolytics | 1.14 (0.93 to 1.40) 0.220 | 0.93 (0.75 to 1.15) 0.498 | 1.13 (0.73 to 1.75) 0.574 |
| Birth due to amniotic infection | 0.90 (0.72 to 1.13) 0.382 | 0.71 (0.55 to 0.91) 0.006 | 0.70 (0.43 to 1.13) 0.574 |
| Birth due to placental abruption | 1.40 (1.02 to 1.90) 0.036 | 1.00 (0.70 to 1.42) 0.987 | 0.78 (0.38 to 1.59) 0.487 |
| Inborn | 1.01 (0.55 to 1.85) 0.982 | 1.14 (0.56 to 2.31) 0.721 | 1.03 (0.32 to 3.35) 0.964 |
| Apgar <7 at 5 min of age | 1.54 (1.24 to 1.91) <0.001 | 1.08 (0.85 to 1.37) 0.516 | 1.63 (1.08 to 2.44) 0.020 |
| Umbilical artery pH <7.1 | 1.43 (0.89 to 2.31) 0.140 | 0.76 (0.43 to 1.33) 0.330 | 1.12 (1.09 to 5.60) 0.801 |
| Early-onset sepsis | 2.06 (1.16 to 3.67) 0.014 | 1.32 (0.71 to 2.45) 0.378 | 2.47 (1.09 to 5.60) 0.031 |
| Treatment with inotropes during the first 24 h of life | 1.86 (1.43 to 2.42) <0.001 | 2.40 (1.82 to 3.16) <0.001 | 1.48 (0.92 to 2.38) 0.109 |
| Lowest mean arterial blood pressure during the first 24 h of life (mm Hg) | 0.97 (0.96 to 0.99) 0.003 | 0.96 (0.94 to 0.98) <0.001 | 0.94 (0.90 to 0.98) 0.003 |
All data are given as ‘OR (95% CI) p’. ORs <1.00 indicate a protective effect of the independent variable. Higher gestational age and higher values for the ‘lowest mean arterial blood pressure during the first 24 h’ were protective. p Values <0.05 are given in bold.