Table 2

Baseline characteristics of babies assessed at 2 years’ corrected age in the two cohorts: before and after the change in nutritional guidelines

Before (n=45)After (n=42)p Value
Gestation (weeks)26 (23–31)26 (24–31)0.4
At birth
 Weight (g)795 (520–980)758 (470–990)0.8
 Length (cm)33.0 (28.5–37.0)33.0 (27.5–36.5)0.8
 Head circumference (cm)23.8 (20.5–26.8)23.2 (20.5–28.2)0.3
 Birth weight z-score−0.2 (−2.6–1.8)−0.5 (−3.5–1.4)0.4
 Weight <10th centile at birth10 (22%)15 (36%)0.2
Male21 (47%)15 (36%)0.4
Definite or probable necrotising enterocolitis3 (7%)5 (12%)0.5
Patent ductus arteriosus30 (67%)32 (76%)0.4
Any intraventricular haemorrhage12 (27%)9 (21%)0.6
Severe intraventricular haemorrhage4 (9%)4 (10%)1
Late-onset sepsis11 (24%)17 (40%)0.2
Any retinopathy of prematurity at discharge43 (96%)35 (83%)0.08
Retinopathy of prematurity grade 3*9 (20%)4 (10%)0.2
CLD20 (44%)25 (60%)0.2
  • Data are median (range) or number (%) as appropriate.

  • Chronic lung disease (CLD), oxygen requirement at 36 weeks’ postconceptional age.

  • Necrotising enterocolitis (NEC), Bell's stage ≥2.18

  • Severe intraventricular haemorrhage, grade 3 or 4.19

  • Late-onset sepsis, positive bacterial culture beyond 7 days after birth in cerebrospinal fluid, urine or blood with clinical signs of infection requiring ≥48 h of antibiotics.

  • *No infant had retinopathy of prematurity (ROP) stage 4.