Table 3

Prevalence by maternal age group for all congenital diaphragmatic hernia (CDH) cases and for isolated CDH cases.*

All cases of CDHIsolated CDH births*
AgeN (%)Prevalence per 10 000 (95% CI)RR (95% CrI)p ValueN (%)Prevalence per 10 000 (95% CI)RR (95% CrI)p Value
<20113 (4.6)2.21 (1.82 to 2.66)1.01 (0.82 to 1.24)0.39064 (3.7)1.25 (0.96 to 1.6)0.84 (0.63 to 1.09)0.302
20–24449 (18.2)2.19 (1.99 to 2.4)1 (reference)309 (17.7)1.51 (1.34 to 1.68)1 (reference)
25–29770 (31.2)2.07 (1.92 to 2.22)0.95 (0.84 to 1.06)551 (31.5)1.48 (1.36 to 1.61)0.97 (0.84 to 1.12)
30–34706 (28.6)2.07 (1.92 to 2.23)0.92 (0.82 to 1.04)512 (29.3)1.5 (1.38 to 1.64)0.96 (0.83 to 1.1)
35+427 (17.3)2.39 (2.17 to 2.63)1.03 (0.89 to 1.17)313 (17.9)1.75 (1.56 to 1.96)1.07 (0.91 to 1.26)
  • *Cases occurring with chromosomal anomalies, genetic syndromes, microdeletions, teratogenic syndromes or in multiple pregnancies were excluded. Several registers were also excluded due to incomplete denominator data (see methods).

  • CI, confidence interval; CrI, credible interval; ex., excluded; RR, relative risk.