Gestational age, wks; median (25th–75th IQ) | 30 (26–37) |
Birth weight, g; median (25th–75th IQ) | 1300 (750–2650) |
PT, s; median (25th–75th IQ) | |
<28 wks | 17.5 (15.6–22.1) |
28–34 wks | 20.0 (15.6–25.0) |
>34 wks | 19.5 (16.3–26.2) |
APTT, s; median (25th–75th IQ) | |
<28 wks | 63 (52–75) |
28–34 wks | 58 (43–70) |
>34 wks | 49 (39–66) |
Fibrinogen, mg/dL; median (25th–75th IQ) | |
<28 wks | 189 (120–289) |
28–34 wks | 196 (126–295) |
>34 wks | 167 (111–253) |
Platelet count, ×106/mL (N=104); median (25th–75th IQ) | 129 (65–220) |
Dose of FFP, mL/kg; mean (±SD) | 16 (4) |
No. of neonates requiring mechanical ventilation (%) | 240/290 (83) |
No. of neonates having patent ductus arteriosus (%) | 101/264 (38) |
No. of neonates requiring catecholamine infusion (%) | 180/290 (62) |
Type of haemorrhage | |
IVH all grades; no. of neonates (%) | 48/257 (18.6) |
IVH grade 3 or 4; no. of neonates (%) | 17/257 (6.6) |
Pulmonary haemorrhage; no. of neonates (%) | 16/290 (5.5) |
Gastrointestinal haemorrhage; no. of neonates (%) | 27/290 (9.3) |
Minor haemorrhage; no. of neonates (%) | 47/290 (16.2) |
Data on patent ductus arteriosus and on IVH were missed in 26 and 33 cases, respectively.
APTT, activated partial thromboplastin time; FFP, fresh frozen plasma; IVH, intraventricular haemorrhage; PT, prothrombin time; wks, weeks of gestational age.