Perinatal characteristics (total subjects=85)
| Male sex, n | 57 (67%) |
| Median birth weight, grams (range) | 3360 (2042–5300) |
| Median Apgar score at 10 min (IQR) | 5 (4, 7) |
| Median first pH, by cord or within 1 h (IQR) | 6.90 (6.78, 6.97) |
| Median first base deficit, by cord or within 1 h, mmol/L (IQR) | −18.5 (−15.0, −23.0) |
| Need for respiratory support at 10 min age, n | 70 (82%) |
| Median age when heart rate first >100/min, minutes (IQR) | 2 (1, 5) |
| Median age at first gasp, minutes (range) | 5 (0, 95) |
| Antenatal sentinel event identified, n | 21 (25%) |
| Suspected clinical seizures, n | 58 (68%) |
| Treated with anticonvulsants, n* | 60 (72%) |
| Received sedation during cooling, n† | 74/81 (91%) |
| Median age at start of aEEG monitoring (range) | 5 h 12 min (15 min to 11 h 20) |
| Median duration of aEEG monitoring (range) | 93 h 55 (6 h 55 to 174 h 57) |
| Any seizures identified on aEEG/EEG, n | 44 (52%) |
| High seizure burden on aEEG/EEG, n | 30 (35%) |
| Burst suppression, continuous low voltage or flat trace in the first 24 h | 42 (49%) |
| Burst suppression, continuous low voltage or flat trace at 48 h of age‡ | 14 (17%) |
| Median age at MRI, days (range) | 9 (4, 35) |
| Severe pattern of injury on MRI (group 1), n | 31 (36%) |
| Survived to discharge home or to local hospital, n | 80 (94%) |
*Data unavailable for 2 subjects.
†Data unavailable for 4 subjects.
‡3 subjects did not have aEEG data at 48 h.