Definitions of diagnoses in babies with test positive pulse oximetry screening
| Congenital pneumonia | Raised inflammatory markers (CRP >10 mg/L) ± positive culture, radiological changes on chest X-ray, oxygen requirement (for longer than 2 h), antibiotics for ≥5 days |
| Meconium aspiration syndrome | History of meconium staining of liquor, respiratory distress, oxygen requirement (for longer than 2 h), radiological changes on chest X-ray |
| Sepsis | Raised inflammatory markers (CRP >10 mg/L) ± positive culture, antibiotics for ≥5 days |
| TTN requiring oxygen | Tachypnoea with radiological changes of fluid retention, oxygen requirement (for more than 2 h), no rise in inflammatory markers or positive culture |
Congenital pneumonia, meconium aspiration syndrome or TTN requiring oxygen were classified as significant respiratory illness.
CRP, C-reactive protein; TTN, transient tachypnoea of the newborn.