Adjusted results for PaCO2 variables in relation to outcome of bronchopulmonary dysplasia/death
| PaCO2 variable | Adjusted OR (95% CI) | p Value |
|---|---|---|
| Max PaCO2 (per 10 mm Hg) | 1.27 (1.12 to 1.44) | 0.0002 |
| PaCO2 category | ||
| Higher SpO2 target | ||
| Hypocapnic | 0.78 (0.48 to 1.3) | 0.34 |
| Hypercapnic | 1.24 (0.67 to 2.29) | 0.49 |
| Fluctuator | 3.28 (1.1 to 9.79) | 0.03 |
| Normocapnic | Reference | – |
| Lower SpO2 target | ||
| Hypocapnic | 1.07 (0.64 to 1.79) | 0.79 |
| Hypercapnic | 1.71 (0.95 to 3.07) | 0.07 |
| Fluctuator | 0.62 (0.23 to 1.69) | 0.35 |
| Normocapnic | Reference | – |
| Average PaCO2 (per 10 mm Hg) | 1.65 (1.24 to 2.21) | 0.0007 |
Interaction term for PaCO2 category×treatment group (higher or lower SpO2) was significant for fluctuators.
PaCO2, arterial partial pressure of carbon dioxide; SpO2, oxygen saturation.