Table 1

Maternal and neonatal characteristics

Early onset sepsis
Possible or proven (%)Not infected (%)Totalp Value
Maternal
Spontaneous preterm labour
 Yes82 (71)487 (49)569<0.0001
 No34 (29)501 (51)535
Clinical chorioamnionitis*
 Yes22 (20)68 (6.9)90<0.0001
 No90 (80)912 (93)1002
Abnormal amniotic fluid†
 Yes20 (18)89 (9.1)1090.006
 No93 (82)891 (91)984
Maternal antibiotics‡
 Yes97 (86)687 (69)7840.0004
 No16 (14)302 (31)318
Maternal GBS status
 Positive24 (21)286 (29)3100.13
 Negative64 (55)461 (47)525
 Unknown28 (24)244 (25)272
Delivery at less than 37 weeks
 Yes98 (84)632 (64)730<0.0001
 No18 (16)359 (36)377
Neonatal
Gender female
 Yes62 (50)487 (45)5490.27
 No61 (50)592 (55)653
Apgar score <7 at 5 min
 Yes84 (68)403 (37)487<0.0001
 No39 (32)675 (32)714
Gestational age (weeks)
 Mean (SD)30.5 (4.6)34.6 (4.0)1202<0.0001
 Median (range)30 [23, 40]34 [24, 42]
Respiratory distress lasting more than 3 h
 Yes112 (91)534 (49)646<0.0001
 No11 (8.9)545 (51)556
Need for surfactant
 Yes76 (62)179 (17)255<0.0001
 No47 (38)900 (83)947
  • *Fever during labour as a temperature greater than 37.5°C on two occasions more than 1 h apart or a temperature >38.0°C.

  • †Meconium-stained or foul-smelling amniotic fluid.

  • ‡Any antibiotics given prior to or during labour with the exception of prophylaxis antibiotics for elective C-section. p Value represents χ2 or adjusted χ2 tests for categorical variables on maternal and neonatal characteristics, respectively, and adjusted t tests for continuous neonatal characteristics.

  • GBS, Group B Streptococcus.