Primary and secondary outcomes
| Outcome | HHHFNC | NCPAP | p Value |
|---|---|---|---|
| EDIN score, cumulative* | 10.7 (3.3) | 11.1 (3.0) | 0.35 |
| Noise, dBA | 70 (10) | 74 (10) | 0.18 |
| Parental assessment | |||
| 1. Child satisfied | 8.6 (1.1) | 6.9 (1.6) | <0.001 |
| 2. Contact and interaction | 9.0 (1.1) | 6.7 (1.6) | <0.001 |
| 3. Possibility to take part in care | 9.1 (1.2) | 8.0 (1.6) | 0.03 |
| TcPCO2 (mean 2 h) kPa | 5.5 (1.1) | 5.5 (1.2) | 0.87 |
| Respiratory rate (mean 24 h) | 41 (7) | 46 (9) | 0.001 |
| FiO2 (mean 24 h) | 21.8 (1.6) | 21.5 (1.1) | 0.06 |
| SpO2 (mean 24 h) | 95 (2) | 95 (2) | 0.41 |
All data are mean (SD).
*Cumulative score based on assessment over three nursing shifts (day, evening, night).
HHHFNC, heated humidified high flow nasal cannulae; NCPAP, nasal continuous positive airway pressure.