Koppel | Reich | Rosati | Arlettaz | Reich | Bakr | Kawalec | de Wahl Granelli | Meberg | Sendelbach | Riede | Ewer | Prudhoe* | Total | 95%CI | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Birth cohort | 1998–99 | 2000–01 | 2000–04 | 2003–04 | 2003–05 | 2004 | 2004–05 | 2004–07 | 2005–6 | 2006–07 | 2006–08 | 2008–09 | 1999–09 | 1998–09 | |
Screened (n) | 11281 | 2114 | 5292 | 3262 | 7962 | 5211 | 27200 | 39821 | 50008 | 15233 | 41445 | 20055 | 29925 | 258809 | |
Timing | >24 h | >24 h | >24 h | <24 h | >24 h | >24 h | At∼24 h | >24 h | <24 h | <24 h | >24 h | <&>24 h | <24 h | ||
Probes | Single | Single | Single | Single | Single | Twin | Single | Twin | Single | Single | Single | Twin | Single | ||
Trigger threshold | <96% | <95% | <95% | <95% | <95% | <95% (†) | <95% | <95% (>3%) | <95% | <96% | <96% | <95% (>2%) | <95% | ||
Single vent | 1/1 | 2/2 | 1/1 | 2/2 | 6/6 | 61 to 100% | |||||||||
HLHS | 3/3 | 2/2 | 2/2 | 3/3 | 3/5 | 1/1 | 5/5 | 1/1 | 20/22 | 72 to 97% | |||||
Tricuspid Atr | 1/1 | 1/1 | 3/4 | 5/6 | 44 to 97% | ||||||||||
Truncus | 1/1 | 2/2 | 3/3 | 1/1 | 1/1 | 2/3 | 10/11 | 62 to 98% | |||||||
DORV | 3/3 | 1/1 | 1/1 | 5/5 | 57 to 100% | ||||||||||
TGA | 1/1 | 2/2 | 6/6 | 11/12 | 8/8 | 4/5 | 7/8 | 6/7 | 45/49 | 81 to 97% | |||||
PA+IVS | 1/1 | 1/1 | 1/1 | 3/3 | 44 to 100% | ||||||||||
PA+VSD | 1/1 | 1/1 | 2/2 | 3/3 | 2/2 | 2/2 | 1/1 | 5/6 | 17/18 | 74 to 99% | |||||
AVSD | 1/2 | 8/9 | 1/2 | 2/4 | 12/17 | 47 to 87% | |||||||||
TAPVC | 2/2 | 1/2 | 1/1 | 1/1 | 1/1 | 4‡/5 | 2/2 | 5/5 | 1/1 | 2‡/2 | 20‡/22 | 70 to 97% | |||
Fallot | 2/3 | 0/3 | 6/8 | 2/4 | 1/10§ | 11/28 | 24 to 58% | ||||||||
CoA/IAA | 0/1 | 1/2 | 1/1 | 0/2 | 3/4 | 4‡/13 | 3‡/6 | 1/4 | 3/7 | 2/10 | 18/50 | 24 to 50% | |||
Ao arch hypoplasia | 1/2 | 1/2 | 9 to 90% | ||||||||||||
Ao Atr/ St | 1/1 | 3/4 | 4/5 | 38 to 96% | |||||||||||
PS | 1/3 | 0/1 | 1/1 | 1‡/1 | 1/1 | 1/5 | 5/12 | 19 to 68% |
*Data from Richmond et al5 is contained within the current study report.
†Pre- and postductal measurements taken, with action demanded if either below 95%. No specified action on percentage difference.
‡Indicates that some of these cases were discharged undiagnosed despite low saturation in the first 24 h of life.
§Includes three cases of tetralogy in term babies diagnosed in the first year of life, but not receiving surgery until the second year of life.
Diagnostic categories follow the hierarchy used by Fyler et al.28
Italics indicates diagnoses considered primary targets for pulse oximetry screening by Kemper et al.12
Ao arch hypoplasia, aortic arch hypoplasia; Ao Atr/St, aortic valve atresia or stenosis; AVSD, atrioventricular septal defect; CoA/IAA, coarctation of the aorta or interrupted aortic arch; DORV, double-outlet right ventricle; Fallot, Fallot's tetralogy; HLHS, hypoplastic left heart syndrome; PA+IVS, pulmonary atresia with intact ventricular septum; PA+VSD, pulmonary atresia with ventricular septal defect; PS, pulmonary stenosis; Single vent, single ventricle; TAPVC, total anomalous pulmonary venous connection; TGA, transposition of the great arteries; Tricuspid Atr, tricuspid atresia; Truncus, truncus arteriosus.