Independent effects of gestational age, birth weight and male gender on various outcomes, and adjusted OR for contrasts between eras, adjusting for gestation, weight and gender
| Variable | OR; 95% CI; p value | ||||
|---|---|---|---|---|---|
| Outcome | Gestation-per week | Birth weight-per 100 g | Male | 1991–92 versus 1997 | 2005 versus 1997 |
| Postnatal corticosteroids | 0.66 (0.59 to 0.74); p<0.001 | 0.69 (0.62 to 0.78); p<0.001 | 1.92 (1.37 to 2.71); p<0.001 | 1.13 (0.76 to 1.70); p=0.54 | 0.41 (0.26 to 0.65); p<0.001 |
| Bronchopulmonary dysplasia (BPD)# | 0.80 (0.73 to 0.87); p<0.001 | 0.84 (0.76 to 0.94); p<0.001 | 1.67 (1.24 to 2.25); p=0.001 | 1.31 (0.90 to 1.89); p=0.16 | 1.54 (1.04 to 2.27); p=0.03 |
| Died before 2 years | 0.93 (0.82 to 1.05); p=0.10 | 0.66 (0.57 to 0.66); p<0.001 | 2.38 (1.52 to 3.72); p<0.001 | 2.05 (1.17 to 3.60); p=0.013 | 1.64 (0.91 to 2.96); p=0.10 |
| Cerebral palsy (CP) | 0.89 (0.76 to 1.04); p=0.13 | 1.15 (0.99 to 1.33); p=0.067 | 1.52 (0.90 to 2.55); p=0.11 | 0.61 (0.34 to 1.11); p=0.14 | 0.65 (0.34 to 1.22); p=0.18 |
| Major disability | 0.90 (0.81 to 1.01); p=0.080 | 0.90 (0.79 to 1.02); p=0.090 | 2.54 (1.72 to 3.78); p<0.001 | 0.66 (0.42 to 1.02); p=0.06 | 0.64 (0.40 to 1.04); p=0.08 |
| Death or CP | 0.89 (0.81 to 0.99); p=0.030 | 0.83 (0.74 to 0.92); p=0.001 | 2.13 (1.49 to 3.04); p<0.001 | 1.20 (0.78 to 1.85); p=0.40 | 1.10 (0.70 to 1.73); p=0.68 |
| Death or major disability | 0.90 (0.82 to 0.98); p=0.018 | 0.79 (0.72 to 0.87); p<0.001 | 2.64 (1.92 to 3.65); p<0.001 | 0.93 (0.63 to 1.36); p=0.70 | 0.81 (0.54 to 1.21); p=0.30 |